精神分裂症患者攻击行为与临床特征的相关性研究

目的 探讨精神分裂症患者攻击行为的相关危险因素.方法 对入院178例精神分裂症患者按入院前有无攻击行为分为攻击组和无攻击组,两组分别从年龄、性别、文化、病程、既往攻击行为等一般情况、简明精神病量表和艾森克个性问卷方面进行单因素对照分析和多因素回归分析.结果 （1）经单因素分析,攻击组病程[（7.73±6.67）年]显著长于非攻击组[（5.22±5.47）年]（t=2.631,P＜0.01）；攻击组BPRS中的敌对猜疑因子得分[（13.73±3.098）分]高于非攻击组[（11.47±3.93）分]（f=4.063,P＜0.01）,焦虑因子得分[（7.18±3.583）分]低于非攻击组[（8.70±3.89）分]（t=2.679,P＜0.01）;EPQ的E量表分攻击组[（11.99±4.340）分]显著高于非攻击组[（10.67±4.293）分]（t=1.990,P＜0.01）；攻击组既往有攻击行为的患者所占比例（71.1％）显著高于非攻击组（16％）（x2=39.082,P＜0.01）.（2） Logistic分析结果显示,BPRS中的敌对猜疑因子和既往攻击行为史进入回归方程.结论 精神分裂症患者攻击行为的发生主要与其精神症状和既往攻击行为史有关,应积极治疗,控制症状并防止病情反复.

The relationship between aggressive behaviors and clinical features in the inpatients with schizophrenia

Objective To explore the relative factors of aggressive behaviors in inpatients with schizophrenic.Methods 178 cases of continuously admitted schizophrenic patients were divided into attack group and non aggressive group according to the aggressive behavior of preadmission.Single factor analysis and multi factor regression analysis was applied to two groups in situation（such as age,gender,education level,course of disease,past aggressive behaviors and so on）,Brief Psychiatric Rating Scale （BPRS） and Eysenck Personality Questionnaire （EPQ）.Results By single factor analysis,attack group had significantly longer course of disease（7.73±6.67） than non aggressive group （5.22 ± 5.47,t =2.631,P＜ 0.01）.The score of hostile suspicious factor in BPRS （13.73 ± 3.098） in attack group was significantly higher than that in nonaggressive group（11.47±3.93） （t=4.063,P＜ 0.01）,but anxiety factor （7.18± 3.583） was significantly lower than that in nonaggressive group （8.70 ± 3.89） （t=2.679,P＜0.01）.The score of E scale of EPQ（11.99±4.340） in attack group was significantly higher than that in nonaggressive group（10.67±4.293） （t=1.990,P＜0.01）.Attack group＇s proportion of patients of previous attacks （71.1％） was significantly higher than that in non aggressive group （16.0％）,（x2 =39.082,P＜ 0.01）.（2） Logistic analysis showed that hostile suspicious factor in BPRS and past aggressive behaviors entered the regression equation.Condusions Aggressive behavior in schizophrenic patients occurs mainly with psychiatric symptoms and the past history of aggressive behavior.The patients should be treated actively to control the symptoms and prevent the disease recurrence.