| 抗病毒口服液的质量标准研究 |
| |
| 引用本文： | 余继英,何林,胡远,孙世明,吴正中.抗病毒口服液的质量标准研究[J].中国药房,2006,17(20):1576-1579. |
| |
| 作者姓名： | 余继英 何林 胡远 孙世明 吴正中 |
| |
| 作者单位： | 四川省人民医院药剂科,成都市,610072 |
| |
| 摘 要： | 目的:建立抗病毒口服液的质量标准。方法:采用薄层色谱法对抗病毒口服液中的金银花、鱼腥草、赤芍和射干进行定性鉴别;以高效液相色谱法对其金银花中的绿原酸进行含量测定。结果:抗病毒口服液的金银花、鱼腥草、赤芍、射干薄层色谱中,在与对照药材相应的位置上显相同颜色的斑点;绿原酸检测浓度在3.66～73.20μg/ml范围内与峰面积积分值线性关系良好(r=0.9998),平均回收率为99.7%(RSD=1.52%)。结论:所建质量标准可用于本品的质量控制。
|
| 关 键 词： | 抗病毒口服液 薄层色谱法 高效液相色谱法 绿原酸 质量标准 |
| 文章编号： | 1001-0408(2006)20-1576-04 |
| 收稿时间： | 11 7 2005 12:00AM |
| 修稿时间： | 01 4 2006 12:00AM |
Study on Quality Standard for Kangbingdu Oral Solution |
| |
| YU Jiying,HE Lin,HU Yuan,SUN Shiming,WU Zhengzhong.Study on Quality Standard for Kangbingdu Oral Solution[J].China Pharmacy,2006,17(20):1576-1579. |
| |
| Authors: | YU Jiying HE Lin HU Yuan SUN Shiming WU Zhengzhong |
| |
| Abstract: | OBJECTIVE:To establish the method for quality control of Kangbingdu oral solution.METHODS:TLC was used to identify 4 Chinese medicines,which were Flos Lonicerae,herba houttuyniae,radix paeoniae rubra and rhizoma belamcandae.HPLC was used to determine the content of chlorogenic acid of Flos Lonicerae.RESULTS:In the TLC of flos lonicerae,Herba houttuyniae,Radix paeoniae rubra and rhizoma belamcandae,spots of same color were identified in the corresponding position.The linear range of chlorogenic acid was 3.66～73.20μg/ml(r=0.9 998).The average recovery was 99.7% and the RSD was 1.52%.CONCLUSION:The method was simple,accurate and with strong specificity and could be used to control the quality of this preparation. |
| |
| Keywords: | Kangbingdu oral solution TLC HPLC Chlorogenic acid Quality standard |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
