Platelet monoamine oxidase activity in Down's syndrome |
| |
| Authors: | Christopher J.,Fowler ,Å sa,Wiberg ,Karl-Henrik, Gustavson Bengt,Winblad |
| |
| Affiliation: | Departments of Pharmacology University of Umeå, Umeå, Sweden;Departments of Pediatrics University of Umeå, Umeå, Sweden;Departments of Pathology, University of Umeå, Umeå, Sweden |
| |
| Abstract: | ![]()
The activity of platelet monoamine oxidase in Down's syndrome cases was significantly lower than that of controls. This difference was found for both males and females, and with tyramine, tryptamine and β-phenethylamine as substrate. The Km values of the monoamine oxidase towards tryptamine as substrate from controls and Down's syndrome patients were similar. |
| |
| Keywords: | Down's syndrome monoamine oxidase platelets |
|
|
