| 山萸肉醇提液的致突变性 |
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| 引用本文： | 张慧珍,宋春花,杨继要,呼世斌,吴逸明. 山萸肉醇提液的致突变性[J]. 癌变．畸变．突变, 2005, 17(3): 187-189 |
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| 作者姓名： | 张慧珍 宋春花 杨继要 呼世斌 吴逸明 |
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| 作者单位： | 郑州大学医学院公共卫生学院,河南,郑州,450052;郑州大学医学院基础医学院,河南,郑州,450052;西北农林科技大学生命科学院,陕西,杨凌,712100 |
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| 摘 要： | 背景与目的:从遗传学角度评价山茱萸果肉醇提物的潜在危害性,为山茱萸开发为保健功能性食品提供科学依据。材料与方法:采用小鼠睾丸染色体畸变试验,小鼠骨髓微核实验以及小鼠精子畸形实验方法。结果:山萸肉醇提物诱发小鼠睾丸染色体畸变实验,诱发小鼠精子畸形实验以及微核实验结果显示,各剂量组与阴性对照相比较,差异均无显著性。结论:山萸肉醇提液对实验动物均没有染色体与细胞水平上的损伤作用,结合其它毒理学资料可以考虑作为新食品资源利用。
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| 关 键 词： | 山萸肉 醇提液 致突变 |
| 文章编号： | 1004-616X(2005)03-0187-03 |
| 修稿时间： | 2004-09-13 |
Mutagenicity of the Matter Extracted from the Pulp of Cornus by Ethanol |
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| ZHANG Hui-zhen,SONG Chun-hua,YANG Ji-yao,HU Shi-bin,WU Yi-Ming. Mutagenicity of the Matter Extracted from the Pulp of Cornus by Ethanol[J]. Carcinogenesis,Teratogenesis and Mutagenesis, 2005, 17(3): 187-189 |
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| Authors: | ZHANG Hui-zhen SONG Chun-hua YANG Ji-yao HU Shi-bin WU Yi-Ming |
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| Abstract: | BACKGROUND&AIM: To check the mutagenicity of the matter extracted from the Pulp of cornus by ethanol. MATERIAL AND METHODS: Chromosome aberration test,micronucleus test of bone marrow cell and sperm shape abnormality test in mice were used in this study. RESULTS: The test result shows that:there have no significant difference between the matter extracted from the pulp of cornus by ethanol and negative control,but has significant difference to positive control. CONCLUSION: The matters extracted has no damage effect on the chromosome and cell levels.It provides science proof on exploiting functional health food of cornus of ficinalis sieb.et Zucc. |
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| Keywords: | pulp of cornus the matter extracted by ethanol mutagenicity |
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