降钙素原及甲状腺激素水平与感染性休克转归的相关性研究

目的：探讨降钙素原（PCT）、甲状腺激素水平与感染性休克（SS）转归的相关性。方法：选取我院2014年4月～2016年4月收治的SS患者，依据预后效果分组：好转组37例，恶化组37例。记录比较两组入住d1、d3、d7及出院/转出或死亡当天血清PCT、FT3及FT4水平变化情况；并评价PCT、FT3、FT4水平与APACHEⅡ评分、SOFA评分的相关性。结果：好转组d3、d7及出院/转出或死亡当天PCT、FT3、FT4水平，均显著优于恶化组同期（P<0.01）；PCT水平与APACHEⅡ评分、SOFA评分，均呈正相关（P<0.01）；FT3、FT4水平与APACHEⅡ评分、SOFA评分，均呈负相关（P<0.01）。结论：SS患者早期检测血清PCT、FT3及FT4水平，并结合APACHEⅡ评分及SOFA评分在评估SS严重程度与判断预后方面效果突出，具有较高临床参考价值。

Calcitonin original and thyroid hormone levels and the correlation of septic shock outcome studies

Objective: To investigate the correlation between the levels of procalcitonin (PCT), thyroid hormone and the cirrhosis of septic shock (SS). Methods:SS patients treated in our hospital from April 2014 to April 2016 were selected and divided into two group according to the prognosis effect:37 cases of the improved group, 37 cases of the deterioration group. The changes of serum PCT, FT3 and FT4 levels were recorded and compared between the two groups in 1d, 3d, 7d, and at discharge/turn-out or on the day of death. And then the correlation among PCT, FT3, FT4 levels and APACHE II score and SOFA score were evaluated. Results: The levels of PCT, FT3, and FT4 in 3d, 7d, and at discharge/turn-out or on the day of death in the improved group were significantly better than those of the deterioration group of the same period (P<0.01) PCT level and APACHE II score, SOFA score, were positively correlated (P<0.01); FT3, FT4 levels and APACHE II score, SOFA score, were negatively correlated (P<0.01). Conclusion: Early detection of serum PCT, FT3 and FT4 levels on SS patients, combined with the APACHE II score and SOFA score has an outstanding effect in assessing the severity and judging the prognosis, with a high clinical reference value.