| 淋巴瘤细胞凋亡调控的分子生物学进展 |
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| 引用本文： | 刘陶文. 淋巴瘤细胞凋亡调控的分子生物学进展[J]. 华夏医学, 2001, 14(3): 396-398 |
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| 作者姓名： | 刘陶文 |
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| 作者单位： | 广西第二人民医院肿瘤研究所, |
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| 基金项目： | 广西卫生厅资助项目 ( No.Z2 0 0 0 44) |
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| 摘 要： | 凋亡或程序性细胞死亡是正常和瘤性淋巴细胞自稳调控的重要机制,众多的细胞凋亡相关蛋白涉及淋巴瘤的发生,bcl-2家庭,capase-3和多药耐药蛋白在淋巴瘤细胞的表达程度与化疗,放疗反应及该病的预后有关。
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| 关 键 词： | 淋巴瘤 细胞凋亡 bcl－2 caspase－3 多药耐药性 分子生物学 |
| 文章编号： | 1008-2409(2001)03-0396-03 |
| 修稿时间： | 2000-08-01 |
Update of Molecular Biology on Regulating Apoptosis of Lymphoma |
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| LIU Tao wen//Institute of Oncology,the Second People''''s Hospital. Update of Molecular Biology on Regulating Apoptosis of Lymphoma[J]. Acta Medicinae Sinica, 2001, 14(3): 396-398 |
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| Authors: | LIU Tao wen//Institute of Oncology the Second People''''s Hospital |
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| Affiliation: | Nanxishan Hospital |
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| Abstract: | Apoptosis or programmed cell death is essential in the pr oc ess of controlling homeostatic mechanism in both normal and neoplastic lymphocyt e.A numerous proteins associated with apoptosis is crucial to oncogenesis of lym phoma.The pattern of expression of bcl 2 family, caspase 3/cpp 32 and multi d r ug resistance glycoprotein in lymphoma is involvement of apoptotic process and r espond to chemotherapy and radiotherapy,as well as the prognosis of this disease . |
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| Keywords: | lymphoma apoptosis bcl 2 Caspase 3 multidrug resistan ce |
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