腹腔镜联合米非司酮治疗子宫内膜异位症的疗效观察

目的探讨腹腔镜联合米非司酮治疗子宫内膜异位症的疗效。方法选择2010年1月～2013年1月在我院住院治疗的子宫内膜异位症患者60例,均行腹腔镜手术,根据术后是否应用米非司酮分为观察组和对照组各30例,观察组术后第2天口服米非司酮,每次12.5mg。每日1次,连用6个月。对照组未予米非司酮治疗。结果观察组的完全缓解率、部分缓解率虽然高于对照组,但组间比较差异无统计学意义（P〉0.05）;观察组术后的复发率仅6.7%,明显低于对照组（P〈0.05）。观察组患者月经恢复时间明显短于对照组,观察组患者恢复排卵时间明显快于对照组（t=2.364、8.358,P〈0.05）。结论腹腔镜联合米非司酮治疗子宫内膜异位症疗效确切,安全性好,复发率低,值得推广和应用。

Efficacy of laparoscopy combined with mifepristone in treatment of endometriosis

Objective To study the efficacy of mifepristone combined laparoscopic in treatment of endometriosis.Methods From January 2010 to January 2013,selected 60 cases of endometriosis patients treated in our hospital according to whether using mifepristone were randomly divided into observation group and the control group, each of 30 patients, the observation group combined mifepristone on the first two days after surgery, 12.5 mg once a time, 1 time a day, once every six months. Control group was not given mifepristone treatment. Results Although the complete remission rate and partial remission rate in the observation group was higher, but the difference was not statistically significant between two groups（P〉0.05）; Postoperative recurrence rate of 6.7% in the observation group was significantly lower than the control group（P〈0.05）. The patients menstrual recovery time was significantly shorter than the control group, recovery time of ovulation in the observation group were significantly faster than that in the control group（t=2.364,8.358, P 〈0.05）. Conclusion Laparoscopic combined with mifepristone in treatment of endometriosis is effective and safety, with lower recurrence rate, worthy of promotion and application.