| 绞股蓝提取液对光老化模型小鼠皮肤组织中SOD活性MDA和HYP含量影响的实验研究 |
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| 引用本文： | 王丽红,吴景东. 绞股蓝提取液对光老化模型小鼠皮肤组织中SOD活性MDA和HYP含量影响的实验研究[J]. 中华中医药学刊, 2006, 24(3): 497-499 |
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| 作者姓名： | 王丽红 吴景东 |
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| 作者单位： | 辽宁中医药大学,辽宁,沈阳,110032 |
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| 摘 要： | 目的:研究内服绞股蓝对紫外线照射引起的无毛小鼠皮肤光老化模型的影响。方法:昆明无毛小鼠随机分成5组,正常组(A)、模型对照灌胃组(B)、低剂量灌胃组(C)、中剂量灌胃组(E)、高剂量灌胃组(F)。模拟UV长期照射,造成皮肤光老化模型。给药组照射同时灌胃绞股蓝提取液。采用病理组织切片制片技术,HE染色以40倍光镜观察真皮结构改变,并以生化分析方法测定SOD活性,HYP及MDA含量。结果:绞股蓝C、D、E组对SOD活性均有提高作用(P<0.05)。D、E组可提高羟脯氨酸含量,降低MDA含量。结论:绞股蓝提取液具有拮抗紫外线照射引起的无毛小鼠皮肤光老化的作用。
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| 关 键 词： | 绞股蓝 皮肤 光老化 超氧化物歧化酶(SOD) 羟脯氨酸(HYP) 丙二醛(MDA) |
| 文章编号： | 1009-5276(2006)03-0497-03 |
| 修稿时间： | 2005-09-30 |
To Investigate G. Pentaphyllum''''s Influence on the Content of HYP and MDA as Well as the Activity of SOD in the Skin of Hairless Photo Aging Mice |
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| WANG Li-hong,Wu Jing-dong. To Investigate G. Pentaphyllum''''s Influence on the Content of HYP and MDA as Well as the Activity of SOD in the Skin of Hairless Photo Aging Mice[J]. Chinese Archives of Traditional Chinese Medicine, 2006, 24(3): 497-499 |
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| Authors: | WANG Li-hong Wu Jing-dong |
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| Abstract: | Objective:Study to take orally to G.pentaphyllum whether in the skin of hairless photoageing mice model has the function or not that project light upon to cause to the ultravioletrays.Methods:Healthy KM hairless micewere divided into sevengroups randomly and gavages respectively,that is negativeControl Group(A),Model Group(B),Model Low-G.Pentaphyllum |
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| Keywords: | G.Pentaphyllum sk in photoage ing superoxide d ismutase(SOD) hydroxyproline(HYP) m alond ialdehyde |
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