连续性肾脏替代疗法治疗多脏器功能障碍综合征90例疗效分析

目的探讨连续性肾脏替代疗法(CRRT)治疗多脏器功能障碍综合征(MODS)的临床疗效。方法选取2009年1月至2010年6月接受CRRT治疗的MODS患者90例,观察治疗前后患者急性生理学和慢性健康评估(APACHEⅡ)评分、生命体征(血压、心率、血氧饱和度)以及电解质、肾功能情况。结果与治疗前比较,全部患者治疗后APACHEⅡ明显下降,差异有统计学意义(P<0.05)。治疗后患者生命体征稳定,各个指标与治疗前比较差异有统计学意义(P<0.05)。与治疗前比较,所有患者治疗后血肌酐、尿素氮、电解质、pH值均得到较好控制,差异有统计学意义(P<0.05)。结论应用CRRT治疗MODS患者可有效改善肾功能,调节酸碱失衡、电解质紊乱,有利于改善患者的预后。

Therapeutic Effect Analysis of Continuous Renal Replacement Therapy in 90 Cases of Multiple Organ Dysfunction Syndrome

Objective To study the clinical therapeutic effects of continuous renal replacement therapy(CRRT)in multipal organ dysfunction syndrom(MODS).Methods 90 MODS patients accepted therapy of CRRT in our hospital from Jan.2009 to Jun 2010.Their APACHEⅡ,vital signs,such as blood pressure,heart rate,arterial blood gas analysis,and renal function,blood electrolyte were observed during course of CRRT.Results After CRRT treatment,vital signs of all patients were stable.The APACHEⅡof patients were obviously declined.The laboratory test results,such as BUN,SCr,blood electrolyte and pH were significantly improved.Compared with the situation before treatment,there was significant difference(All P<0.05).Conclusion Application of CRRT in patients with MODS can be effective in improving renal function,regulating acid-base imbalance,electrolyte disorders and prognosis of patients.