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多潘立酮治疗婴儿胃食管反流相关性肺炎的疗效观察
引用本文:卫海燕,王凌飞,古建平. 多潘立酮治疗婴儿胃食管反流相关性肺炎的疗效观察[J]. 儿科药学杂志, 2009, 15(1)
作者姓名:卫海燕  王凌飞  古建平
作者单位:河南省郑州市儿童医院,河南,郑州,450052;河南省郑州市儿童医院,河南,郑州,450052;河南省郑州市儿童医院,河南,郑州,450052
摘    要:
目的:观察多潘立酮治疗婴儿胃食管反流相关性肺炎的效果.方法:45例2~8月确诊为胃食管反流相关性肺炎的婴儿,随机分为治疗组26例和对照组19例,对照组予改变体位和少量多次进食等方法,治疗组在对照组的基础上加用多潘立酮混悬液0.2 mg/(kg·次),一日4次,分别于早、中、晚餐及夜间10点喂奶前15~30 min服用,疗程2周.结果:治疗组显效、有效分别为11例和13例,总有效率91.6%;对照组显效、有效分别为5例和7例,总有效率63.2%,两组比较差异具有统计学意义(X2=5.83,P<0.05).治疗组和对照组住院天数分别为(10.62±2.4)d、(15.23±5.2)d,差异有统计学意义(t=3.99,P<0.05).治疗组未见明显不良反应.结论:多潘立酮治疗婴儿胃食管反流相关性肺炎经济安全有效.

关 键 词:多潘立酮  胃食管反流病  婴儿  肺炎

Observation of the Effect of Domperidone on Infants with Pneumonia Related with Gastro Esophageal Reflux
WEI Hai-yan,WANG Ling-fei,GU Jian-ping. Observation of the Effect of Domperidone on Infants with Pneumonia Related with Gastro Esophageal Reflux[J]. Journal of Pediatric Pharmacy, 2009, 15(1)
Authors:WEI Hai-yan  WANG Ling-fei  GU Jian-ping
Affiliation:WEI Hai-yan,WANG Ling-fei,GU Jian-ping (Zhengzhou Children's Hospital of Henan Province,Henan Zhengzhou 7450052,China)
Abstract:
Objective:To observe the effect and safety of domperidone in treatment of infants with pneumonia related with gastro esophageal reflux. Methods: Forty-five infants with pneumonia related with gastro esophageal reflux were divided into two groups randomly. The control group were treated with anti-infective, respiratory management, diet and body position, the treatment group were treated with domperidone (0.2 mg/kg, 4 dose every day) in addition to those of the control group. Results: The clinical symptoms an...
Keywords:Domperidone  Gastro esophageal reflux disease  Infant  Pneumonia  
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