| 安徽省县级医院药品不良反应1944例原因分析 |
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| 引用本文： | 柳立新,杨冬梅,刘俊,刘建军.安徽省县级医院药品不良反应1944例原因分析[J].蚌埠医学院学报,2015,39(7):943-946. |
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| 作者姓名： | 柳立新 杨冬梅 刘俊 刘建军 |
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| 作者单位： | 1.1. 安徽医学高等专科学校 药学系, 安徽 合肥 230601;2.2. 安徽省第二人民医院 药学部, 安徽 合肥 230012 |
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| 基金项目： | 安徽省卫生厅医学科学研究项目(13YC002) |
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| 摘 要： | 目的:分析安徽省县级医院药品不良反应(ADR)报告特点及规律,促进临床合理用药。方法:对9家县级医院2012和2013年度上报的ADR报告进行分类和分析。结果:1 944例ADR报告中,给药途径主要为静脉注射(73.8%);累及器官和临床表现主要为皮肤及附件损害(30.3%);药物品种主要为抗菌药物(38.7%);2年度9家县级医院报告ADR的给药途径、累及器官或系统、引起ADR药物品种和不同医院报告病例数构成差异均有统计学意义(P结论:ADR的发生与给药方式、药品种类有关,ADR监测和报告制度在县级医院执行差异较大。
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| 关 键 词： | 药品不良反应 县级医院 合理用药 |
| 收稿时间： | 2015-03-22 |
Retrospective analysis of 1 944 adverse drug reaction case reports of county hospitals in Anhui province |
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| Institution: | 1.1. Department of Pharmacy, Anhui Medical College, Hefei Anhui 230601;2.2. Department of Pharmacy, Anhui No.2 Province People's Hospital, Hefei Anhui 230012, China |
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| Abstract: | Objective:To analyze the characteristics and regularities of the adverse drug reactions( ADR) in county hospitals of Anhui province,for improving the rational use of drug in clinic. Methods:A total of 1 944 cases of ADR reports collected from nine county level hospitals of Anhui province from 2012 to 2013 were statistically classified and analyzed. Results:The main cause of ADR was originated from intravenous administration ( 73. 8%);damaging the skin and its appendages was the main lesion in ADR cases (30. 3%);about 38. 7% of ADR cases were mainly caused by using antimicrobial drugs;the difference of the drug delivery route, organs or systems involved,type of drugs and the number of reported cases in different hospital has statistical significance(P<0. 01). Conclusions:The occurrence of ADR related to the routs of drug delivery and the type of drug,ADR monitoring and reporting system in county hospital execute differently. |
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| Keywords: | adverse drug reaction county level hospital rational use of drugs |
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