| 血栓调节素与系统性红斑狼疮疾病活动相关性研究 |
| |
| 引用本文： | 韩锋,齐文成.血栓调节素与系统性红斑狼疮疾病活动相关性研究[J].天津医科大学学报,2000,6(3):322-324. |
| |
| 作者姓名： | 韩锋 齐文成 |
| |
| 作者单位： | 韩锋（天津市第一中心医院风湿免疫科）;齐文成（天津市第一中心医院风湿免疫科）;张菁（天津市第一中心医院风湿免疫科）;刘丽（天津市第一中心医院风湿免疫科） |
| |
| 摘 要： | 目的：检测系统性红斑狼疮和原发性血管炎患者血浆血栓素水平，探讨ＴＭ与ＳＬＥ活动的相关性及作为血管炎标记的意义。方法：采用双抗体夹心ＥＬＩＳＡ法测定２１例ＳＬＥ，７例血管炎患者和１９例正常人的血浆ＴＭ水平。结果用ＳＰＳＳ软件进行分析。结果：与正常人相比。活动期ＳＬＥ患者及血管炎患者血浆ＴＭ水平显著高于正常对照（Ｐ〈０．０１）；静止期ＳＬＥ虱血浆ＴＭ水平与正常对照组之间无显著性差异。结论：ｓＴＭ可作为
|
| 关 键 词： | 系统性红斑狼疮 血管炎 血栓调节素 |
| 文章编号： | 1006-8147(2000)03-322-03 |
| 修稿时间： | 2000年4月24日 |
Correlative analysis of thrombomodulin and activity of SLE |
| |
| HAN Feng,QI Wen-cheng,ZHANG Jing,LIU Li.Correlative analysis of thrombomodulin and activity of SLE[J].Journal of Tianjin Medical University,2000,6(3):322-324. |
| |
| Authors: | HAN Feng QI Wen-cheng ZHANG Jing LIU Li |
| |
| Abstract: | Objective To investigate the plasma thrombomodulin(TM) levels in patients with SLE or primary vasculitis and its roles in the progression of diseases. Methods: 21 SLE patients, 7 primary vasculitis patients and 19 normal controls were chosen and the sTM levels were detected by sandwich ELISA. Results:Compared to the normal controls, the plasma TM levels were significantly higher in patients with primary vesculitis or active SLE. There was no statistical difference between inactive SLE patients and normal controls. Conclusion: TM may be a specific marker for primary vesculitis and the measurement of plasma TM level is a useful indicator for monitoring disease activity in SLE patients. |
| |
| Keywords: | Lupus erythematosus systmetic vesculitis thrombomodulin |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
