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Octreotide as first-line treatment for women with metastatic breast cancer
Authors:James N. Ingle MD  Carl G. Kardinal  Vera J. Suman  James E. Krook  Alan K. Hatfield
Affiliation:(1) Mayo Clinic and Mayo Foundation, 55905 Rochester, MN, USA;(2) Ochsner Community Clinical Oncology Program (CCOP), 70121 New Orleans, LA, USA;(3) Duluth CCOP, 55805 Duluth, MN, USA;(4) Carle Cancer Center CCOP, 61801 Urbana, IL, USA;(5) Mayo Clinic, 200 First Street SW, 55905 Rochester, MN, USA
Abstract:
Summary Octreotide is a synthetic somatostatin analogue which has shown inhibitory activity against human breast cancer cells in culture. Ten patients with metastatic breast cancer and no prior hormonal therapy exposure received octreotide at 150 mgrg subcutaneously thrice daily. No objective responses were observed and the median time to treatment failure was short at 57 days.
Keywords:octreotide  metastatic breast cancer
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