Abbreviated Antibiotic Therapy for Clinical Chorioamnionitis: A Randomized Trial

Simple observation may he adequate therapy for patients with clinical chorioamnionitis after vaginal delivery. This study involves 41 subjects who delivered vaginally and had chorioamnionitis. Subjects were prospectively assigned in a randomized, double-blind fashion to either a continued antibiotic or placebo group. Postpartum observation without antibiotics in select patients with chorioamnionitis was supported by equivalent results in the two groups.