Distribution of cholecystokinin (CCK) in the rat lower brain stem nuclei |
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| Authors: | Margery C. Beinfeld Miklos Palkovits |
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| Affiliation: | 1. Department of Pharmacology, St. Louis University School of Medicine, 1402 South Grand Boulevard, St. Louis, MO 63104, USA;2. National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20205, U.S.A. |
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| Abstract: | ![]()
The cholecystokinin (CCK) concentration in individual brain stem nuclei of rat was determined using the Palkovits punch method19 and the CCK RIA3. CCK has a unique distribution in the brain stem, unlike other neuropeptides and biogenic amines8,19. In general, the CCK levels in the brain stem are 5–20% of rat cerebral cortex. The colliculi, midbrain central gray, nucleus of the solitary tract, and the interpeduncular nucleus had the highest CCK content (2.7-1 ng CCK mg protein). |
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| Keywords: | cholecystokinin radioimmunoassay brain stem nuclei |
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