| 低剂量电离辐射对免疫器官CuZn－SOD和Se－GSH－Px活性的影响 |
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| 摘 要： | 本研究观察低剂量Ｘ射线照射后，离体和在体大鼠胸腺和脾细胞ＣｕＺｎ一ＳＯＤ和Ｓｅ一ＧＳＨ一Ｐｘ活性的变化。结果表明，离体脾细胞经３００或５００ｍＧｙ５Ｒ后１２ｈ，两种酶活性都明显增高；大鼠全身１５０～５００ｍＧｙ照后２４ｈ，脾细胞ＣｕＺｎ一ＳＯＤ活性也明显增高。上述结果提示，低剂量照射后脾细胞抗氧化酶活性增高可能是一种抗辐射损伤的保护性反应。
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| 关 键 词： | 低剂量辐射，免疫器官，超氧化物歧化酶，谷胱甘肽过氧化物酶 |
Effects of low dose radiation on on Cuzn-SOD and Se-GSH-Px activities of immune organs |
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| Sun Tiehua,Gong Shouliang,Zhang Ming,et al. Effects of low dose radiation on on Cuzn-SOD and Se-GSH-Px activities of immune organs[J]. Journal of Jilin University: Med Ed, 1996, 0(2) |
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| Authors: | Sun Tiehua Gong Shouliang Zhang Ming et al |
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| Affiliation: | Department of Radiation Biology |
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| Abstract: | The present study was designed to observe the changes of CtiZn一SOD and Se一GSH一Px activities of thymocytles and splenocytes after low dose X-irradiation in rats in vito and in vivo.Both enzymes of splenocytes in creased significantly 12h after the irradiation with 300 or 500 mGy invitro CuZn一SOD actvity of splehocytes also increased significantly 24h after whole一body irradiationwith 150～500 mGy.These results suggest that the increase of splenocyte antilipoperoxidase activityafter the irradiation may be a protective response of radiation-resistant damage. |
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| Keywords: | low dose radiation immune organs CuZn一SOD Se一GSH一Px |
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