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| 附子石油醚、氯仿提取物对虚寒模型大鼠肝组织LDH、SDH活性的影响 | |
| 引用本文： | 杨富梅,韩冰冰,滕佳林,刘珊,刘一洋. 附子石油醚、氯仿提取物对虚寒模型大鼠肝组织LDH、SDH活性的影响[J]. 山东中医药大学学报, 2011, 0(6): 527-528 |
| 作者姓名： | 杨富梅 韩冰冰 滕佳林 刘珊 刘一洋 |
| 作者单位： | 山东中医药大学; |
| 基金项目： | 国家重点基础研究发展计划(973计划)课题(编号:2007CB512601) |
| 摘 要： | 目的:研究附子石油醚提取物、附子氯仿提取物对虚寒模型大鼠肝组织乳酸脱氢酶(LDH)、琥珀酸脱氢酶(SDH)活性的影响。方法:用生石膏、龙胆草、黄柏、知母水煎液造虚寒型大鼠模型,再用附子石油醚提取物、附子氯仿提取物治疗,用分光光度计法测定肝组织中LDH、SDH的活力。结果:与空白对照组比较,虚寒模型组大鼠肝组织LDH活力明显升高(P<0.05),SDH活力明显降低(P<0.05);附子氯仿提取物可显著降低肝组织LDH活力(P<0.01),附子石油醚提取物、附子氯仿提取物可显著升高肝组织SDH活力(P<0.01)。结论:附子石油醚提取物、附子氯仿提取物可拮抗虚寒型大鼠肝组织LDH活力的升高、SDH活力的下降,从而改善大鼠的能量代谢。 |
| 关 键 词： | 附子石油醚提取物 附子氯仿提取物 虚寒证 模型大鼠 肝组织 LDH SDH |
Effects of aconite petroleum ether extract,aconite chloroform extract on LDH and SDH activities in liver of deficiency-cold rats |
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| YANG Fu-mei,HAN Bing-bing,TENG Jia-lin,LIU Shan,LIU Yi-yang. Effects of aconite petroleum ether extract,aconite chloroform extract on LDH and SDH activities in liver of deficiency-cold rats[J]. Journal of Shandong University of Traditional Chinese Medicine, 2011, 0(6): 527-528 | |
| Authors: | YANG Fu-mei HAN Bing-bing TENG Jia-lin LIU Shan LIU Yi-yang |
| Affiliation: | YANG Fu-mei,HAN Bing-bing,TENG Jia-lin,LIU Shan,LIU Yi-yang(Shandong University of Traditional Chinese Medicine,Jinan 250355,China) |
| Abstract: | Objective:To study effects of aconite petroleum ether extract,aconite chloroform extract on lactic dehydrogenase(LDH) and succinate dehydrogenase(SDH) activities in liver of deficiency-cold rats.Methods:The models were made by decoction with gypsumgentian,cork and anemarrhena,be treated with aconite petroleum ether extract,aconite chloroform extract.The activeties of LDH and SDH in liver were determined by spectrophotometer.Results:Compared with the control group,LDH activity was significantly increased(P<0... |
| Keywords: | aconite petroleum ether extract aconite chloroform extract deficiency-cold syndrome model rat liver LDH SDH |
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