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| 超氧化物歧化酶和脂质过氧化物丙二醛在犬肾移植中的变化分析 | |
| 引用本文： | 左利群,张肖红,谷艳丽. 超氧化物歧化酶和脂质过氧化物丙二醛在犬肾移植中的变化分析[J]. 中华器官移植杂志, 1994, 0(4) |
| 作者姓名： | 左利群 张肖红 谷艳丽 |
| 作者单位： | 武汉同济医科大学器官移植研究所 |
| 摘 要： | 本文测定了２１只犬在正常、肾移植前和肾移植恢复血流后１小时，血中超氧化物歧化酶（ＳＯＤ）活性和脂质过氧化物丙二醛（ＭＤＡ）含量的变化。结果发现：在肾移植前和肾移植恢复血流后１小时与正常时相比，血中ＳＯＤ活性明显下降（Ｐ＜０．００１），同时血中ＭＤＡ含量显著升高（Ｐ＜０．００１），尤以移植后恢复血流１小时为甚。提示了在肾移植过程中，加入一定的自由基清除剂等，对术后恢复将有重要的作用，而在肾保存中移植后加入抗氧化剂至关重要。 |
| 关 键 词： | 超氧化物歧化酶，脂质过氧化物丙二醛，犬肾移植 |
Alterations of SOD activity and MDA Content in Canine Blood During Kidney Transplantation |
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| Zuo Li-qun, Zhang Xiao-hong, Gu Yan-li,et al.. Alterations of SOD activity and MDA Content in Canine Blood During Kidney Transplantation[J]. Chinese Journal of Organ Transplantation, 1994, 0(4) | |
| Authors: | Zuo Li-qun Zhang Xiao-hong Gu Yan-li et al. |
| Abstract: | Blood samples from 21 dogs were collected before,after kidney procurement and 1 hour after kidney transplantation. SOD activity and MDA content in the blood were detected. The results showed that SOD activities both after kidney procurement and 1 hour after kidney transplantation were significantly lower than those before kidney procurement (P< 0. 001). While the MDA concen-trations were increased after procurement, and were especially high 1 hour after kidney transplantation (P<0. 001). It has suggested that the anti-free-radocals agents might have beneficial effects on the recovery of graft function. |
| Keywords: | Malondialdehyde Superoxide dismutase Canine kidney transplantation |
| 本文献已被 CNKI 等数据库收录！ | |