首页 | 本学科首页   官方微博 | 高级检索  
     

葛根芩连汤治疗慢性牙周炎的临床疗效观察
引用本文:赵兵,王丹,魏润生,和明春,王丽茹,马陈民,张秀红. 葛根芩连汤治疗慢性牙周炎的临床疗效观察[J]. 湖南师范大学学报(医学版), 2017, 14(3). DOI: 10.3969/j.issn.1673-016X.2017.03.003
作者姓名:赵兵  王丹  魏润生  和明春  王丽茹  马陈民  张秀红
作者单位:1. 唐山市中医医院口腔科,唐山,063000;2. 华北理工大学口腔医院,唐山,063000;3. 唐山市工人医院,唐山,063000;4. 唐山市丰润区第二医院,唐山,063000;5. 唐山市丰南区医院,唐山,063000;6. 迁安市人民医院,迁安,064000;7. 唐山市中心血站,唐山,063000
基金项目:河北省中医药管理局2016年指令课题
摘    要:
目的:探讨葛根芩连汤治疗慢性牙周炎的临床疗效.方法:将60例慢性牙周炎患者分为观察组和对照组,每组30例.对照组采用常规牙周基础治疗.观察组在对照组基础上,口服葛根芩连汤.于治疗前后,检测两组患者探诊深度(PD)、附着丧失(AL)的水平变化;采集患者龈沟液,采用酶联免疫吸附测定法检测龈沟液中肿瘤坏死因子(TNF-a)、白介素6(IL-6)、白介素8(IL-8)的水平变化.结果:两组治疗后PD、AL均显著降低;治疗后,观察组的PD、AL显著低于对照组,差异有统计学意义;两组治疗后TNF-a、IL-6、IL-8均显著降低;治疗后,观察组的TNF-a、IL-6、IL-8显著低于对照组,差异有统计学意义;观察组的疗效显著优于对照组,差异有统计学意义.结论:葛根芩连汤能显著改善慢性牙周炎患者的临床症状,减轻炎症反.

关 键 词:葛根芩连汤  慢性牙周炎  炎性因子

To observe the clinical curative effect of Gegenqinlian Decoction in the treatment of chronic periodontitis
Zhao Bing,Wang Dan,Wei Run-sheng,He Ming-chun,Wang Li-ru,Ma Chen-min,Zhang Xiu-hong. To observe the clinical curative effect of Gegenqinlian Decoction in the treatment of chronic periodontitis[J]. Journal of Hunan Normal University(Medical Science), 2017, 14(3). DOI: 10.3969/j.issn.1673-016X.2017.03.003
Authors:Zhao Bing  Wang Dan  Wei Run-sheng  He Ming-chun  Wang Li-ru  Ma Chen-min  Zhang Xiu-hong
Abstract:
Objective To investigate the clinical effect of Gegenqinlian Decoction in the treatment of chronic periodonti-tis.Methods60 cases of chronic periodontitis were divided into observation group and control group,30 cases in each group. The control group was treated with routine periodontal treatment. The observation group on the basis of the control group, oral administration of Gegenqinlian decoction. Before and after treatment, the levels of PD and AL were detected in two groups of patients. The levels of TNF-a, IL-6 and IL-8 in gingival sulcus fluid were detected by enzyme linked immunosorbent assay. Results The two groups after treatment, AL, PD were significantly reduced. After treatment, the PD and AL of the observation group were significantly lower than that of the control group. The difference was statistically significant. TNF-a, IL-6 and IL-8 were significantly decreased after treatment in the two groups. After treatment, the TNF-a, IL-6 and IL-8 of the observation group were significantly lower than those of the control group. The difference was statistically significant. The curative effect of the observation group was significantly better than that of the control group, the difference was statistically significant.Conclu-sion Gegenqinlian decoction can significantly improve clinical symptoms of patients with chronic periodontitis, anti inflammation.
Keywords:gegenqinlian decoction  chronic periodontitis  inflammatory factors
本文献已被 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号