Alcohol can inhibit effect of IL-4 on activated murine B cells |
| |
| Authors: | Marlene Aldo-Benson Linda Pratt Joyce Hardwick |
| |
| Affiliation: | Department of Medicine, Indiana University School of Medicine, Indianapolis 46202-5103. |
| |
| Abstract: | ![]()
Ethanol addition to B lymphocytes in vitro inhibits antigen-induced antibody secretion and antigen-induced cell proliferation. We tested the hypothesis that ethanol can inhibit the effect of interleukins on B-cell proliferation by adding ethanol to in vitro functional assays for IL-2 and IL-4. Ethanol does not inhibit IL-2-induced B-cell differentiation, but it does inhibit IL-4-induced B-cell proliferation and IL-4-induced Ig class switching. |
| |
| Keywords: | Ethanol IL-4 B-lymphocyte proliferation |
| 本文献已被 SpringerLink 等数据库收录！ |
