| 激光照射脑组织损伤区细胞色素氧化酶的改变 |
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| 引用本文： | 张相彤 吴振铎. 激光照射脑组织损伤区细胞色素氧化酶的改变[J]. 哈尔滨医科大学学报, 1996, 30(4): 347-349 |
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| 作者姓名： | 张相彤 吴振铎 |
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| 作者单位： | [1]一院神经外科 [2]电镜室 |
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| 摘 要： | 本实验选用３５只家兔经ＣＯ２激光照射后，利用酶组织化学方法－锇黑法直接，动态，定量地观察脑组织损伤区水肿外带中线粒体的细胞色素氧化酶的变化。随激光照射时间延长，线粒体内细胞色素氧化酶逐渐脱失，超微结构逐渐破坏。在相同条件下，激光照射２秒，４秒后，在地塞米松组和激光照射组之间线粒体内细胞色素氧化酶脱失有极显著差异，而激光照射６秒之后，两组虽有差异但不甚显著，说明ＤＸＭ对激光照射后的脑组织损伤区具有保
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| 关 键 词： | 脑损伤 细胞色素氧化酶 激光疗法 CO2激光 |
Study on Changes of Cytochrome Oxidase Activity in Mitochondia in the Cerebral Damaged Tissue Exposed to CO 2 Laser |
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| Zhang Xiangtong et al. Study on Changes of Cytochrome Oxidase Activity in Mitochondia in the Cerebral Damaged Tissue Exposed to CO 2 Laser[J]. Journal of Harbin Medical University, 1996, 30(4): 347-349 |
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| Authors: | Zhang Xiangtong et al |
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| Abstract: | Cytochrome oxidase activity in mitochondria in periedema zone of the cerebral damaged tissue exposed to CO 2 laser irradiation in 35 rabbits of both sexes was investigated with histochemistry directly and quantitatively.Cytochrome oxidase activity in mitochondria was reduced graduatly and ultrastructure was damaged graduatly with duration time of CO 2 laser irradiation.In the case of same pD.reduction of cytochrome oxidase activity in mitochondria in DXM groups and laser groups found obviously different ( P <0 001) after 2,4 seconds of CO 2 laser irradiation.Reduction of cytochrome oxidase activity in mitochondria in DXM groups and laser groups was different ( P <0 05) after six seconds of CO 2 laser irradiation,but it not found obviously difference.The results showed that damaged area of CO 2 laser irradiation on cerebral tissue was protected with DXM.The more mildly cerebral tissue damaged,the more apparently cerebral tissue was protected with DXM. |
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| Keywords: | Laser Cerebral tissue damage Cytochrome oxidase Dexamethasone. |
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