结缔组织病合并肺动脉高压患者的右室功能:多普勒组织成像技术研究

目的采用多普勒组织成像技术分析结缔组织病（CTD）合并肺动脉高压（PAH）患者右室功能和各项指标之间的关系。方法34例CTD合并PAH患者以及32例无PAH的对照者进行超声心动图检查,评价右室大小和功能。同时采用多普勒组织成像（DTI）评价右室侧壁、室间隔和左室侧壁的应变曲线及三尖瓣环的运动速度。结果DTI结果显示与对照组相比,CTD合并PAH患者的右室应变峰值、三尖瓣环收缩速度和舒张早期速度显著降低,同时存在右室不同步。结论DTI技术可以反映CTD合并PAH患者的右室功能状况。

Right Ventricular Function in Patients with Connective Tissue Diseases and Pulmonary Arterial Hypertension:Doppler Tissue Imaging

Objective To study the right ventricular function in the patients with connective tissue diseases(CTD)and pulmonary arterial hypertension(PAH)by Doppler tissue imaging(DTI).Methods The right ventricular function in 34 patients with CTD and PAH and 32 age-and sex-matched patients without PAH were prospectively evaluated by echocardiographic parameters.Results Compared with the control subjects,patients with CTD and PAH had statistically lower peak longitudinal right ventricular wall strain,tricuspid annular systolic velocity and early diastolic velocity.Right ventricular dyssynchrony was present in patients with CTD and PAH.Conclusions DTI can evaluate the right ventricular function in patients with CTD and PAH.