| CC趋化因子受体与炎症性肠病 |
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| 引用本文： | 叶小研,钟英强. CC趋化因子受体与炎症性肠病[J]. 胃肠病学, 2014, 0(1): 50-53 |
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| 作者姓名： | 叶小研 钟英强 |
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| 作者单位： | 中山大学孙逸仙纪念医院消化内科,510120 |
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| 基金项目： | 本课题由国家自然科学基金面上项目（81370499）资助 |
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| 摘 要： | 炎症部位白细胞聚集和活化是炎症性肠病(IBD)的重要特征,趋化因子受体是趋化白细胞的重要调节因子。在IBD中,多种趋化因子受体表达上调,触发多种炎症反应。本文就CC趋化因子受体(CCR)在IBD中的作用及其作为IBD治疗靶点的可能性作一综述。
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| 关 键 词： | 趋化因子 CC 受体 CCR 炎症性肠病 |
CC Chemokine Receptors and Inflammatory Bowel Disease |
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| YE Xiaoyan,ZHONG Yingqiang. CC Chemokine Receptors and Inflammatory Bowel Disease[J]. Chinese Journal of Gastroenterology, 2014, 0(1): 50-53 |
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| Authors: | YE Xiaoyan ZHONG Yingqiang |
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| Affiliation: | . Department of Gastroenterology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou (510120) Correspondence to： ZHONG Yingqiang, Email： zhongyingqiang@21cn, com |
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| Abstract: | Leucocytes aggregation and activation at inflammatory sites are important features of inflammatory bowel disease （IBD）, and ehemokine receptors are the essential regulatory factors for chemoattracting leucocytes. Many chemokine receptors are up-regulated and trigger various types of inflammation in IBD. In this review article, the role of CC chemokine receptors （CCR） in IBD and its potential to be the therapeutic target of IBD was discussed. |
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| Keywords: | Chemokines, CC Receptors, CCR Inflammatory Bowel Disease |
| 本文献已被 CNKI 维普 等数据库收录！ |
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