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硫酸吗啡控释片治疗癌症疼痛的临床观察
引用本文:顾玉红,杜佳新,李晶,李南南. 硫酸吗啡控释片治疗癌症疼痛的临床观察[J]. 中国药物依赖性杂志, 2005, 14(3): 203-204
作者姓名:顾玉红  杜佳新  李晶  李南南
作者单位:1. 哈尔滨医科大学附属肿瘤医院,哈尔滨,150040
2. 哈尔滨医科大学附属第一临床医学院,哈尔滨,150001
3. 哈尔滨红十字中心医院,哈尔滨,150076
摘    要:目的:观察硫酸吗啡控释片对晚期癌症镇痛的效果。方法:采用开放试验方法,对100例中、重度癌痛患者进行治疗。硫酸吗啡控释片单片剂量为30mg,每12h给药一次,在用药过程中根据疼痛缓解程度调整剂量。结果:本组100例患者中显效65例,显效率65·0%,有效32例,有效率32·0%,无效3例,无效率3·0%,总有效率为97·0%(97/100)。结论:硫酸吗啡控释片治疗癌症疼痛疗效确切,有效率高。是中、重度癌痛的首选药品,现已应用于临床。

关 键 词:硫酸吗啡控释片  癌痛  临床观察
收稿时间:2004-12-10
修稿时间:2004-12-10

CLINICAL OBSERVATION OF ANALGESIC EFFECT OF MORPHINE SULFATE CONTROLLED- RELEASE TABLETS ON CANCER PAIN
GU Yuhong,DU Jiaxin,LI Jing,LI Nannan. CLINICAL OBSERVATION OF ANALGESIC EFFECT OF MORPHINE SULFATE CONTROLLED- RELEASE TABLETS ON CANCER PAIN[J]. Chinese Journal of Drug Dependence, 2005, 14(3): 203-204
Authors:GU Yuhong  DU Jiaxin  LI Jing  LI Nannan
Abstract:Objective: To observe the analgesic effect of morphine sulfate controlled-release tablets on cancer patients at late period.Methods:100 cancer patients with moderate and severe pain were recruited in an open experiment. Each of the patients was administered one tablet(30 mg) every 12 h,and the dosage was adjusted individually according to the analgesic effect.Results:65.0% (65 patients)obtained obvious effect,32.0% (32 cases)got partial effect and 3.0% (3 cases) showed no effect. The total effective rate was 97.0%.Conclusion:The analgesic effect of morphine sulfate controlled-release tablets on cancer pain is obvious. It can be a first choice for the management of moderate and severe cancer pain.
Keywords:morphine sulfate controlled-release tablets  cancer pain  clinical observation
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