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Measurement of subclinical carotid atherosclerosis may help in predicting risk for stroke in patients with diabetes
Authors:David Della-Morte  Camillo Ricordi  Fiorella Guadagni  Tatjana Rundek
Affiliation:1. Department of Neurology, Miller School of Medicine, University of Miami, Clinical Research Building, 1120 NW 14th Street, Rm 1363, Miami, FL, 33136, USA
2. Department of Advanced Biotechnologies and Bioimaging, IRCCS San Raffaele, Rome, Italy
3. Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL, USA
Abstract:Diabetes is one of the most important risk factor for stroke and cardiovascular disease (CVD), especially in young patients. The control of classical vascular risk factors failed in terms of prevention of stroke in patients with diabetes. In addiction, in these patients the glycemic control showed a benefit on microvascular disease but lacked an established benefit in macrovascular disease. Therefore, implementations of effective stroke prevention strategies appear necessary in patients with diabetes. Ultrasound surrogate or intermediate markers of carotid atherosclerosis include carotid intima-media thickness (cIMT), carotid plaque (CP), and carotid stiffness (STIFF) have been demonstrated to increase in patients with diabetes and to be able to predict risk for stroke. In this editorial we discuss the opportunity to prevent the onset of vascular disease in their “preclinical or subclinical” stage in patients with higher risk for stroke such as diabetic patients.
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