| 中药活性成分诱导HeLa细胞凋亡作用机制的实验研究近况 |
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| 引用本文： | 尹龙平,李刚,方刚. 中药活性成分诱导HeLa细胞凋亡作用机制的实验研究近况[J]. 中国中医药现代远程教育, 2008, 6(11) |
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| 作者姓名： | 尹龙平 李刚 方刚 |
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| 作者单位： | 1. 山西省科学技术情报研究所,030001
2. 广西中医学院,030001 |
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| 摘 要： | 目的了解中药活性成分诱导HeLa细胞凋亡作用机制的实验研究近况。方法复习国内外相关文献,综述中药活性成分诱导HeLa细胞凋亡的作用机制。结果中药活性成分不仅能够通过阻断细胞周期来诱导细胞凋亡、还能通过影响Fas/Fasl系统、p53基因蛋白、Bcl-2基因家族、caspase家族的表达等来实现这一过程。结论中药活性成分在诱导宫颈癌HeLa细胞凋亡中起重要作用,其作为宫颈癌的一种辅助治疗手段,有着广阔的临床应用前景。
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| 关 键 词： | 中药 HeLa细胞 细胞凋亡 作用机制 |
Progress on the Experiment Study of Mechanism of Action of TCM Bioactive Component Induced HeLa Cell Apoptosis |
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| Yin longping,LI gang,Fang gang. Progress on the Experiment Study of Mechanism of Action of TCM Bioactive Component Induced HeLa Cell Apoptosis[J]. Chinese Medicine Modern Distance Education of China, 2008, 6(11) |
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| Authors: | Yin longping LI gang Fang gang |
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| Affiliation: | Yin LP LI G Fang G; |
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| Abstract: | Objective To investigate the recent advances on the experiment study of mechanism of Action of traditional chinese medicine (TCM) bioactive bomponent induced HeLa cell apoptosis. Methods Reviewing the achievements about these documents ,this paper tries to summarize mechanism of actions that ti is in inducing HeLa cell apoptosis. Results It not only could induce cell apoptosis through preventing period of the cell ,but also bring about this process from influencing the expression of Fas/ FasL system、P53 gen... |
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| Keywords: | traditional Chinese medicine Hela cell apop tosis mechanism of action |
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