| 通心络胶囊对缺血性脑血管病患者血清C反应蛋白及颈动脉斑块的影响 |
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| 引用本文： | 李勇,胡蓓蕾,管璇,代允义,王小同,宋兴伟.通心络胶囊对缺血性脑血管病患者血清C反应蛋白及颈动脉斑块的影响[J].中国中医药科技,2010,17(1):10-11. |
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| 作者姓名： | 李勇 胡蓓蕾 管璇 代允义 王小同 宋兴伟 |
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| 作者单位： | 温州医学院第二附属医院·温州 325000 |
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| 摘 要： | 目的：观察通心络胶囊对缺血性脑血管病患者C反应蛋白（C—reactive protein，CRP）及颈动脉斑块的影响。方法：将87例患者随机分为通心络组（43例）和立普妥组（44例），治疗3月后，观察两组患者总胆固醇、低密度胆固醇、甘油三酯、CRP及颈动脉内中膜厚度和斑块大小的变化。结果：两组患者治疗后血CRP明显下降（P〈0．05），颈动脉内中膜厚度明显变薄（P〈0．05），斑块明显缩小（P〈0．05）。通心络组治疗后总胆固醇、低密度胆固醇和甘油三酯虽有下降，但差异无显著意义（P〉0．05）。立普妥组治疗后。总胆固醇、低密度胆固醇明显下降，与治疗前比较有显著性差异（P〈0．05）。治疗后两组组间比较，除总胆固醇和低密度胆固醇下降有显著性差异（P〈0．05），余指标无显著性差异。结论：通心络抗颈动脉粥样斑块作用机制可能与降低血清CRP有关。
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| 关 键 词： | 动脉硬化/中医药疗法 通心络／治疗应用 颈动脉 人类 |
EFFECTS OF TONGXINLUO CAPSULE ON SERUM C-REACTIVE PROTEIN AND CAROTID PLAQUE OF PATIENTS WITH ISCHEMIC VASCULAR DISEASE |
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| LI Yong,HU Bei-lei,Guan Xuan,et al.EFFECTS OF TONGXINLUO CAPSULE ON SERUM C-REACTIVE PROTEIN AND CAROTID PLAQUE OF PATIENTS WITH ISCHEMIC VASCULAR DISEASE[J].Chinese Journal of Traditional Medical Science and Technology,2010,17(1):10-11. |
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| Authors: | LI Yong HU Bei-lei Guan Xuan |
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| Institution: | LI Yong,HU Bei-lei,Guan Xuan,et al(The Second Hospital Affiliated with Wenzhou Medical College,Wenzhou 325000) |
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| Abstract: | Objective: To observe the effects of tongxinluo capsule on C-reactive protein and carotid plaque in patients with ischemic vascular disease.Methods: 87 cases with ischemic vascular disease were divided into tongxinluo and western medicine groups, observing the changes of serum TC,TG,LDL,CRP and determining the intima-media thickness of carotid and plaques area after treated 3 monthes.Results: CRP level of two groups was lowered significantly, intima-media thickness of carotid was thinner than that before tr... |
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