定量检测PCT、CRP在产科ICU患者感染诊断及预后判断中的应用评价

目的:探讨血清降钙素原(procalcitonin,PCT)、C-反应蛋白(CRP)水平在产科重症监护病房(in-tensivecareunit,ICU)患者感染的诊治及其预后判断中的临床价值。方法:将产科ICU患者分为重症感染组、一般感染组、对照组,检测其血清PCT、CRP水平。结果:重症感染组、一般感染组分别与对照组比较,PCT、CRP值均有显著增高(P<0.01);重症感染组与一般感染组比较,其PCT阳性率有显著增高(P<0.05),但CRP阳性率无显著增高(P>0.05);重症感染组、一般感染组中,PCT阳性率均较hs-CRP阳性率高,差别有统计学意义(P<0.05);PCT浓度与患者的预后密切相关,一般感染组较重症感染组预后效果良好。结论:血清PCT值对产科危重患者感染诊断及判断患者预后具有重要的临床意义。

The assessment of PCT and CRP quantitative detection for diagnosis and prognosis of infections in maternity ICU patients

Objective: To discuss the clinical value of PCT,CRP quantitative detection in diagnosis and prognosis of infections in maternity ICU patients.Methods: PCT and CRP were measured in patients in the maternity ICU,who were divided into severe infection group,general infection group and non-infection group.Results: The levels of PCT and CRP in severe infection group and general infection group were significantly higher than those in non-infection group(P<0.01);The positive rate of PCT in severe infection group was significantly higher than that of general infection group(P<0.05),but CRP had no obvious difference(P>0.05);The positive rates of PCT in sever infection group and general infection group were all significantly higher than the rates of CRP(P<0.05);There was significant correlation between serum PCT and prognosis.Conclusion: PCT has important clinical guiding significance on the diagnosis of infections and prognosis evaluation in the maternity ICU patients.