HPV感染在尖锐湿疣及外阴和宫颈上皮内瘤变病变中的分布 |
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引用本文: | 王力,李振丰,吴勇军,唐仪,李筝,赵毅,伍镇江,. HPV感染在尖锐湿疣及外阴和宫颈上皮内瘤变病变中的分布[J]. 中国医学工程, 2012, 0(4): 22-24 |
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作者姓名: | 王力 李振丰 吴勇军 唐仪 李筝 赵毅 伍镇江 |
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作者单位: | 怀化医学高等专科学校附属怀化市第三人民医院皮肤性病科;湘潭市第一人民医院病理科 |
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基金项目: | 湘潭市科技计划项目(ZJ103004) |
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摘 要: | 目的探讨HPV感染在尖锐湿疣和上皮内瘤变(包括外阴和宫颈)病变中的分布情况。方法通过HPV基因分型检测对330例尖锐湿疣和250例上皮内瘤变病变进行了HPV6、11、42等低危型及16、18、31、33、39、45、52、56、58等高危型DNA检测。结果 330例的尖锐湿疣组织中:274例为HPV6/11型(83.0%),46例为HPV16/18型(13.9%);250例上皮内瘤变病变组织中,8例为HPV6/11型(3.2%),167例为HPV16/18型(66.8%)。结论尖锐湿疣感染的HPV类型以HPV6、11为主,上皮内瘤变病变HPV类型以HPV16、18为主。
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关 键 词: | 人乳头瘤病毒(HPV) 尖锐湿疣 上皮内瘤变 |
The distribution of HPV infection in the condylomata acuminate and the vulva and cervix intraepithelial neoplasia |
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Affiliation: | WANG Li1,LI Zhen-feng2,WU Yong-jun2,et al(1.The Third People’s Hospital of Huaihua,Huaihua,Hunan 418000,P.R.China; 2.The First People’s Hospital of Xiangtan,Xiangtan,Hunan 411101,P.R.China) |
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Abstract: | 【Objective】 To investigate the distribution of HPV infection in the condylomata acuminate and intraepithelial neoplasia(including the vulva and cervix).【Methods】 Detect HPV6,11,42 low-risk type and 16,18,31,33,39,45,52,56,58 high-risk DNA in 330 cases condylomata acuminate and 250 cases intraepithelial neoplasia lesions by HPV genotyping.【Results】 Out of 330 cases condylomata acuminate organization: 274 cases were HPV6/11 type(83.0%),46 cases were HPV16/18 type(13.9%);of the 250 intraepithelial neoplasia group,8 cases were HPV6/11 type(3.2%),167 cases were HPV16/18 type(66.8%).【Conclusion】 The main HPV types of condylomata acuminate infection were HPV6,11;intraepithelial neoplasia infected HPV types were HPV16,18 based. |
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Keywords: | human papillomavirus(HPV) condylomata acuminate intraepithelial neoplasia |
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