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肢端恶性黑素瘤局部切除疗效观察
引用本文:张宝军,叶庆佾,邓军,郝飞,郝进,胡嘉念. 肢端恶性黑素瘤局部切除疗效观察[J]. 第三军医大学学报, 2006, 28(19): 1992-1993
作者姓名:张宝军  叶庆佾  邓军  郝飞  郝进  胡嘉念
作者单位:第三军医大学西南医院皮肤科,重庆市皮肤性病研究所,重庆,400038;第三军医大学西南医院全军烧伤研究所,创伤、烧伤与复合伤国家重点实验室,重庆,400038
摘    要:
目的 观察21例肢端恶性黑素瘤(acral malignant melanoma,AMM)局部切除后疗效.方法 7例切除后直接缝合;13例较大损害,切除后植皮,切除范围距病灶0.5~3 cm;1例甲周损害截趾.结果 病理肢端原位黑素瘤8例全部存活;侵袭性黑素瘤13例,存活11例,死亡2例,5~11年存活率84.6%.结论 肢端恶性黑素瘤(AMM)依据损害形态,初步确定是原位或侵袭性,再确定切除范围,侵袭性恶性黑素瘤(MM)术后5~11年存活率为84.6%;原位恶性黑素瘤术后存活率100%.

关 键 词:肢端恶性黑素瘤  手术
文章编号:1000-5404(2006)19-1992-02
收稿时间:2005-10-15
修稿时间:2005-10-152006-05-27

Therapeutic effect of local resection for acral malignant melanoma
ZHANG Bao-jun,YE Qing-yi,DENG Jun,HAO Fei,HAO Jin,HU Jia-nian. Therapeutic effect of local resection for acral malignant melanoma[J]. Acta Academiae Medicinae Militaris Tertiae, 2006, 28(19): 1992-1993
Authors:ZHANG Bao-jun  YE Qing-yi  DENG Jun  HAO Fei  HAO Jin  HU Jia-nian
Affiliation:1 Department of Dermatology; 2 State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burns, Southwest Hospital, Third Military Medieal University, Chongqing 400038, China
Abstract:
Objective To observe the curative effects of local excision on malignant melanoma arising from foot. Methods In 21 cases of acral malignant melanoma, 7 cases of minor damage were dealt with interrupted suture directly after excision, 13 cases of comparatively large damage were treated with skin grafting after excision, one case underwent toe amputation because of periungual lesions. Results Eight cases of acral malignant melanoma in situ survived. Eleven among 13 cases of invasive acral malignant melanoma survived and 2 died, with a survival rate of 84.6% within 5 to 11 years. Conclusion The nature of melanoma was first decided, then the resection margin was determined. Our practice shows the survival rate within 5 - 11 years from invasive malignant melanoma is 84.6% and the survival rate from malignant melanoma in situ is 100%.
Keywords:acral malignant melanoma   operation
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