卵巢女性化性索间质性肿瘤39例临床病理分析

重新复查我院1960～1980年收治原诊为卵巢女性化性索间质性肿瘤39例的病理切片,可疑者再切片作特殊染色,复查后纠正了11例误诊病例,对确诊的28例的临床表现、病理特征、随访结果及预后等进行了分析。讨论了误诊病例的病理后,建议此类肿瘤中的粒层细胞瘤命名为“恶性粒层细胞瘤”,其恶性度与细胞分级密切相关,预后与卵巢外扩散及治疗是否彻底相关。

CLINICAL PATHOLOGIC ANALYSIS OF 39 CASES PREVIOUSLY DIAGNOSED AS "THE FEMALE SEX CORD-STROMAL TUMORS" OF OVARY

39 hospitalitalized cases previously diagnosed as "the fama-le sex cord-stromal tumors of ovary", including granulosa cell tumors,theca cell tumors and granulosa-theca cell tumors were reviewed in thisarticle. From 1960 to 1980 the authors re-examined all the biopsy-sec-tions, and re-sectioned with special staining for those doubted cases. 11cases were found misdiagnosed previously. The authors analysed the misdiagnosed cases and suggested the ra-tional nomenclature of "Malignant Granulosa Cell Tumor" in stead of theinproper traditional term "granulosa cell tumor" based upon the quanlityand pathogenesis of these kind of tumors. Integrating with the clinical data,the authors made some comments onthe therapeutic principles and the factors influencing the prognosis ofthese tumors,emphasizing the importance of histologic typing and cyto-logic differentiation during histopathologic examination, surgical-pathologicstaging during exploratory laparatomy, the radical excision of tumor withadjunctive therapy and the long-term follow-up.