经尿道电切术合并吡柔比星膀胱灌注治疗女性腺性膀胱炎的临床疗效

目的：探讨采用经尿道电切术合并吡柔比星膀胱灌注治疗女性腺性膀胱炎的临床疗效。方法苏州市市立医院北区泌尿外科于2009年7月至2012年12月期间采用经尿道电切术合并吡柔比星膀胱灌注法治疗40例女性腺性膀胱炎。结果所有手术均取得成功，平均手术时间约（22.4±6.3）min，术后留置尿管平均时间（4.2±2.1）d，平均住院时间（5.3±2.5）d。经综合治疗后，40例病例中痊愈21例（52.5％），好转15例（37.5％），无效4例（10.0%）。总有效（治愈＋好转）率达92.3％。术中术后未出现严重出血、膀胱穿孔、尿失禁等并发症，治疗期间亦无患者出现肝肾功能异常。结论经尿道电切术联合吡柔比星膀胱灌注是治疗女性腺性膀胱炎及预防复发和恶变的有效方法。

Clinical Benefits of Using Transurethral Resection Incorporated with Pirarubicin Perfusion for Cystitis Glandularis in Females

Objective To investigate the clinical beneifts of using transurethral resection incorporated with pirarubicin perfusion for cystitis glandularis in females. Method 40 female inpatients suffered with cystitis glandularis were received the therapy of transurethral resection incorporated with pirarubicin perfusion in Urology Department of Suzhou Municipal Hospital during a period from Jul 2009 to Dec 2012. Results The surgical for 40 patients was performed successfully with mean operation time of （22.4±6.3）min, mean indwelling catheter time of（4.2 ±2.1）d, and mean hospitalization time of（5.3 ±2.5）d. After the comprehensive treatment, among 40 cases, 21 cases（52.5%）were cured, 15 cases（37.5%）were improved, and 4 cases（10.0%） were failed. The total effective（cure＋improved）rate is 92.3%. During and after the surgical operation, no severe bleeding, perforation of the bladder, urinary incontinence, or any other complications was observed, and during treatment no patient occurred liver and kidney dysfunction. Conclusion It is concluded that transurethral resection incorporated with pirarubicin perfusion is a preferred and effective therapy for cystitis glandularis in females.