Mivacurium chloride for anesthesia in day surgery

Anesthetic techniques for day surgery must foresee a prompt recovery of alertness, ambulation and alimentation. The aim of our study is to evaluate mivacurium chloride in outpatient general anesthesia. Twenty patients, aged 18–55 years, American Society of Anesthesiologists (ASA) class I–II, undergoing surgical procedures were studied. Mivacurium (0.2 mg/kg) was administered to provide neuromuscular relaxation and endotracheal intubation was performed. Additional doses of 0.1 mg/kg mivacurium were given to maintain neuromuscular block, monitored by Relaxograph (Datex). In all patients, mivacurium provided satisfactory conditions for tracheal intubation after a mean time of 120 ± 15 s. Spontaneous recovery after the last dose of mivacurium was obtained in a mean time of 15 min. No side-effects or significant hemodynamic changes were recorded. The incidence of histamine-related side-effects was low. Mivacurium produces spontaneous recovery of neuromuscular block in a short time and shows some ideal properties for anesthesia in day surgery.