| 原发性高血压患者尿微量白蛋白与高敏C反应蛋白及脉压 |
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| 引用本文： | 刘国勤,于瑞霞,颜波,孟春,郭战利. 原发性高血压患者尿微量白蛋白与高敏C反应蛋白及脉压[J]. 高血压杂志, 2008, 0(6) |
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| 作者姓名： | 刘国勤 于瑞霞 颜波 孟春 郭战利 |
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| 作者单位： | 潍坊医学院附属医院心内科; |
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| 摘 要： | 目的探讨原发性高血压(EH)患者尿微量白蛋白与高敏 C 反应蛋白(hsCRP)及脉压(PP)的关系。方法 EH 患者60例根据尿微量白蛋白(MAU)含量分为高血压尿微量白蛋白组(MAU 组,n=30)含量和高血压尿正常白蛋白组(NMAU 组,n=30)及健康对照组30例。测定各组 MAU、hscRP 及 PP 等,并进行比较。结果MAU 组的 hsCRP 及 PP 均高于 NMAU 组及对照组(P 均<0.05),EH 患者 hsCRP(r=0.42,P<0.05)及 PP(r=0.62,P<0.05)与 MAU 均呈正相关(P<0.05)。偏相关分析矫正年龄、收缩压(SBP)、舒张压(DBP)、血糖等因素后 hsCRP(r=0.26,P<0.05),PP(r=0.32,P<0.05)仍然保持与尿白蛋白排泄量(UAE)相关。结论合并MAU 的 EH 患者体内 hsCRP 增高,脉压增大,EH 患者肾损害与 hsCRP 及 PP 水平有关。
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| 关 键 词： | 原发性高血压 尿微量白蛋白 C反应蛋白 脉压 |
High-sensitivity C-reactive Protein,Pulse Pressure and Microalbuminuria in Patients with Essential Hypertension |
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| LIU Guoqin YU Rui-xia YAN Bo MENG Chun GUO Zhan-li. High-sensitivity C-reactive Protein,Pulse Pressure and Microalbuminuria in Patients with Essential Hypertension[J]. Chinese Journal of Hypertension, 2008, 0(6) |
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| Authors: | LIU Guoqin YU Rui-xia YAN Bo MENG Chun GUO Zhan-li |
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| Affiliation: | LIU Guoqin YU Rui-xia YAN Bo MENG Chun GUO Zhan-li.Department of Cardiology,Affiliated Hospital of Weifang Medical College,Weifang 261031,China |
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| Abstract: | Objective To investigate the relationship between high-sensitivity C-reactive protein(hsCRP), pulse pressure(PP) and microalbuminuria(MAU) in patients with essential hypertension.Methods Consecutive 60 patients with essential hypertension were classified based on the MAU level:patients with MAU(n=30) and the group of patients with normoalbuminuria(NMAU,n=30) with 30 healthy subjects as control.MAU,hsCRP,PP were determined.Results The level of hsCRP and pulse pressure in MAU group were higher than those in N... |
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| Keywords: | Hypertension Microalbuminuria C-reactive protein Pulse pressure |
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