脑血管病激光血管内照射治疗前后血液流变学及血脂指标对比研究

使用低能量Ｈｅ－Ｎｅ激光血管内照射（ＩＬＩＢ）治疗脑血管病（ＣＶＤ）４５ 例。治疗前和疗程结束后，均进行血液流变学指标和胆固醇（ｃｈ）、甘油三脂（ＴＧ） 及纤维蛋白原（Ｆｉｂ）等测定。结果表明：ＩＬＩＢ治疗ＣＶＤ确能使ηｂＨ、ηｖＬ、ＲＶ、ηｐ及 Ｆｉｂ明显下降（ｐ＜０．０１－０．００１）。而对ＨＣＴ、ＥＳＲ、ＥＳＲ－ｋ和Ｃｈ、ＴＣ等则无显著 影响（ｐ＞０．０５）。由此，说明其ηｂ下降主要由于ηｐ、Ｆｉｂ的降低及红细胞变形性增 强所致。故提出在使用ＩＬＩＢ治疗ＣＶＤ时最好先行血液流变学检测。其对高粘血浆 型胶红细胞变形性下降型的疗效必优于细胞高压积型。

THE STUDIES OF HEMORHEOLOGICAL INDEXES BLOOD LIPID AND FIBRINOGEN AFTER THE TREATMENT OF CVD WITH ILIB

This article reported the studies of the treatment of 45 cases of cerebral vascular diseases (CVD) with Intravascular Laser Lrradiatwn of blood (ILIB). 7 inderxes of hemorheology, blood lipid and Fibrinogen were measured in 45 cases with CVD by ILIB befor and after treatment. They were controlled and analysed. The results of the study showed that there was distinctly decreased whole blood viscosity under high and low shear, whole blood reductive and plasma viscosity and fibrinogen after the treatment with ILIB (p < 0. 01- 0. 001). There was no Significant difference in Hematocrit (HcT), erythrosyte sedimentation rate (ESR), K of ESR equation (ESR - k) and blood lipid with ILIB befor and after (p> 0. 05). We consider that the decrease of whole blood viscosity are due to the decrease of plasma viscosity and fibrinogen and the increase of erythrosity deformability. we consider that hemorheology should be tested before the treatment of CVD with ILIB. The treatment effect of high viswsity type of plasma and the decrease type of the deformability of red blood cells is better than that of the increase type of hematocrit with ILIB.