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Metabolic Syndrome and Hypogonadism
Affiliation:1. Department of Family, Community, and Preventive Medicine, University of Arizona College of Medicine- Phoenix, Family and Community Medicine Residency, North Country Healthcare, 2920 North Fourth Street, Flagstaff, AZ 86004, USA;2. Department of Family Medicine, University of Tennessee Graduate School of Medicine, 1924 Alcoa Highway, Box U-67, Knoxville, TN 37920, USA;3. Department of Family, Community, and Preventive Medicine, University of Arizona College of Medicine–Phoenix, 1300 North 12th Street, Suite 605, Phoenix, AZ 85006, USA;1. Men’s Health Boston, Department of Surgery (Urology), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA;2. Boston University Medical Center, Boston, MA, USA;3. Heartlands Hospital, Birmingham, United Kingdom;4. Robert Hague Centre for Diabetes and Endocrinology, Barnsley Hospital, NHS Foundation Trust, Barnsley, United Kingdom;5. Department of Oncology and Metabolism, The Medical School, University of Sheffield, Sheffield, United Kingdom;6. Department of Urology, University of Miami Miller School of Medicine, Miami, FL, USA;1. Mediteknology, Spin-off of the National Council of Research, Via Arnesano, 73100 Lecce, Italy;2. CNR NANOTEC, Institute of Nanotechnology, Via Monteroni, 73100, Lecce, Italy;3. Department of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 103, 41125 Modena, Italy;1. Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Ta-Pei Road, Niao-Sung, Kaohsiung 83305, Taiwan;2. Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Ta-Pei Road, Niao-Sung, Kaohsiung 83305, Taiwan;3. Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan
Abstract:
Metabolic syndrome (MetS) is a complex entity and continues to be a source of medical controversy. The most important pathogenic factors are insulin resistance and visceral obesity. The clinical heterogeneity of the syndrome results from its significant influence on protein, glucose, and fat metabolism, cellular growth and differentiation, endothelial function, atherosclerotic disease, and inflammation. MetS is linked to a number of urologic diseases. This article reviews its relationship with hypogonadism.
Keywords:Metabolic syndrome  Hypogonadism  Testosterone
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