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正交试验优选愈肝宁贴剂制备工艺
引用本文:陆燕萍,曾庆祥,陈文珍,吴小秋. 正交试验优选愈肝宁贴剂制备工艺[J]. 中国医药导报, 2008, 5(24): 48-49
作者姓名:陆燕萍  曾庆祥  陈文珍  吴小秋
作者单位:1. 深圳市龙岗区人民医院,广东深圳,518172
2. 广东药学院,广东广州,510006
3. 广东省梅州市嘉应学院,广东梅州,514031
摘    要:目的:优选出愈肝宁贴剂的制备工艺。方法:以用膏量、固化时间、干燥温度、干燥时间为因素,在三个水平上,以初黏力、剥离强度和皮肤残留现象为指标,用正交试验法优选出最佳制备工艺。结果:以用膏量(7.6±0.1)g/100cm2、固化时间24h、干燥温度60℃、干燥时间3.5h为最佳制备工艺。结论:最佳制备条件所制备的愈肝宁贴剂质量稳定。

关 键 词:愈肝宁贴剂  正交试验法  制备工艺

Preparation proless of Yuganning-patch by Orthogonal optimization
LU Yan-ping,ZENG Qing-xiang,CHEN Wen-zhen,WU Xiao-qiu. Preparation proless of Yuganning-patch by Orthogonal optimization[J]. China Medical Herald, 2008, 5(24): 48-49
Authors:LU Yan-ping  ZENG Qing-xiang  CHEN Wen-zhen  WU Xiao-qiu
Affiliation:LU Yan-ping, ZENG Qing-xiang,CHEN Wen--zhen, WU Xiao-qiu (1.Longgang People's Hospital, Shenzhen 518172,China;2.Guangdong College of Pharmacy, Guangzhou 510006,China;3. Jiaying College,Meizhou 514031,China)
Abstract:Objective: To optimize the Yuganning-Preparation of transdermal patches. Methods: The use of paste, curing time, temperature drying, drying time for the factors in the three level to the early Nianli, skin peel strength and residual phenomenon of indicators, using orthogonal test to select the best prepared. Results:The use of paste (7.6±0.1) g/100 cm^2, curing time 24 h, drying temperature 60℃, the drying time of 3.5 h were the best prepared. Conclusion: The best of the conditions of Yuganning-patch quality is stable.
Keywords:Yuganning-patch  Orthogonal experiment  Preparation process
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