| 莫沙必利联合帕罗西汀治疗功能性消化不良的疗效 |
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| 引用本文： | 方和金.莫沙必利联合帕罗西汀治疗功能性消化不良的疗效[J].热带医学杂志,2009,9(8). |
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| 作者姓名： | 方和金 |
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| 作者单位： | 广东省中山市沙溪隆都医院,中山,528471 |
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| 摘 要： | 目的观察莫沙必利联合帕罗西汀治疗功能性消化不良的临床疗效。方法将112例功能性消化不良患者随机分为治疗组和对照组(各56例)。两组均给予莫沙必利5 mg,每日3次口服;治疗组在此基础上加用帕罗西汀20 mg/d,晨服,疗程均为4周。结果治疗组的显效率(67.9%)和总有效率(89.3%)均优于对照组(分别为41.1%和69.6%,P<0.01和P<0.05)。治疗组治疗后的HAMA和HAMD评分均显著低于对照组(P均<0.01)。治疗组在治疗后3月的复发率(12.5%)也明显低于对照组(30.4%,P<0.05)。结论莫沙必利联合帕罗西汀治疗功能性消化不良疗效好,不良反应少。
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| 关 键 词： | 功能性消化不良 莫沙必利 帕罗西汀 |
Efficacy of Combination of Paroxetine and Mosapride on the Treatment of Functional Dyspepsia |
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| FANG He-jin.Efficacy of Combination of Paroxetine and Mosapride on the Treatment of Functional Dyspepsia[J].Journal Of Tropical Medicine,2009,9(8). |
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| Authors: | FANG He-jin |
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| Institution: | The People's Hopital of Longdu;Shaxi;Guangdong;Zhongshan 528471;China |
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| Abstract: | Objective To observe the efficacy of mosapride combined with paroxetine on treating functional dyspepsia(FD).Method 112 cases with FD were divided randomly into treatment group and control group.Both groups received oral treatment of mosapride 5mg tid,but the treatment group also took paroxetine 20mg / d for 4 weeks.Result The improving rate and the total effectiveness rate of treatment group were significantly higher than those of control group(69.6% vs 41.1%,89.3%% vs 69.6%,respectively,P<0.01 and P<0.05)... |
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| Keywords: | functional dyspepsia mosapride paroxetine |
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