血液流变学在原发性肺癌和转移性肺癌的变化特性探讨

目的:探讨原发性肺癌与转移性肺癌患者血液流变学值变化的特性。方法:选择我院住院肺癌患者55例,并分为原发性肺癌组26例;转移性肺癌组29例;健康对照组50例。采用国产血液粘度计分别测定各组全血粘度、血浆粘度、红细胞压积、红细胞聚集指数、纤维蛋白元。结果:肺癌组血液流变学各参数明显高于健康对照组,差异具统计学意义,t=2.903-13.593,P<0.001,P<0.01;而原发性肺癌组血液流变学各参数,除血浆粘度外均明显高于转移性肺癌组,差异具统计学意义P<0.001,P<0.01;且上两组血液流变学各指标较之健康对照组均明显增高,差异具统计学意义P<0.001,P<0.01。结论:血液流变学值的检测对肺癌的诊断、治疗、预后的评估具有一定的临床价值。

The Study of Hemorheologic Characters Between Patients with Primary and Metastatic Lung Cancer

Objective:To study the changing of hemorheologic indexes between patients with primary and metastatic lung cancer.Methods:We chose 55 cases with lung cancer for study group,among which 26 cases were primary lung cancer and 29 cases were metastatic lung cancer.At the same time me chose 50 healthy people for control group.Methods:Viscosity of whole blood(AVWB),viscosity of plasma(VP)and other hemorheologic indexes were detected.Results:All hemorheologic indexes of lung cancer group were significantly higher than those of control group.All hemorheologic indexes of primary lung cancer group except viscosity of plasma(VP) were higher than metastatic lung cancer group.The difference had statistical meaning.Conclusion:Measurement of hemorheologic indexes may have specifically clinical value in diagnosis,treatment and prognosis of lung cancer.