The role of oxygen free radicals in craniocerebral injury

Serum LPO content was measured by means of TBA in 41 patients suffering from craniocerebral injury in present study. The relationships between OFR and progressing course of craniocerebral injury, level of LPO and patient condition of an injury and prognosis were analysed. Results showed that serum LPO increased obviously in 24 hours after injury. The more severe the condition of an injury was, the higher the serum LPO content was, the worse prognosis would be. Serum LPO content increased statistically in group of death in 24 to 72 hours after injury, while it didn't change significantly in group of survival. The author suggest that the reaction of OFR enhanced after craniocerebral injury, and which was an important factor giving rise to secondary brain injury. Measurement of serum LPO content plays an important role in estimating the patients condition of injury and their prognosis.