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内皮素与脑梗死
引用本文:金启建,赵明祥. 内皮素与脑梗死[J]. 贵阳医学院学报, 2001, 26(4): 308-309
作者姓名:金启建  赵明祥
作者单位:贵阳医学院附院神经科
摘    要:
目的 :检测脑梗死病人的内皮素 - 1(ET - 1)水平 ,研究ET - 1与脑梗死的关系。方法 :检测脑梗死病人ET - 1的水平 ,并与正常对照组比较。结果 :脑梗死病人的ET - 1明显高于正常对照组水平 (U =13.45 ,P<0 0 1) ,还发现ET - 1与高血压、糖尿病、高血脂症有一定的关系。结论 :ET - 1的增高是脑梗死发病的内源性危险因素之一 ,ET - 1的增高不但与脑梗死的发病有关而且与脑梗死的发展有关

关 键 词:脑梗塞  内皮  缩血管肽类  糖尿病  高脂血症
文章编号:1000-2707(2001)04-0308-02
修稿时间:2001-06-08

Relationship between Endothelin-1 and Cerebral Infarction
JIN Qi jian,ZHAO Ming xiang. Relationship between Endothelin-1 and Cerebral Infarction[J]. Journal of Guiyang Medical College, 2001, 26(4): 308-309
Authors:JIN Qi jian  ZHAO Ming xiang
Abstract:
Objective:To measure endothelin-1 in patients with acute cerebral infarction and study the relationship between endothelin-1 and cerebral infarction.Methods: We have measured endothelin-l in 57cases with acute cerebral infarction,and have made control study with 30 healthy people.Results: There is a significant difference between the two groups (U=13.45, P<0.01),and ET-1 is also found related to hypertension,hyperlipemia and diabetes.Conclusion: Endothelin is one of the risk factors of cerbral infarction.Increase of endothelin-1 in plasma is associated with cerebral infarction,and seems to be involved in the pathophysiology of acute cerebral infarction.
Keywords:cerebral infarction  endothelins  diabetes mellilus  hyperlipidemia
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