| 急性冠状动脉综合征患者血清可溶性E-选择素和白介素-10水平的变化及其与冠状动脉病变程度的相关性 |
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| 引用本文： | 汤凤英,马礼坤,石增刚,桑更生.急性冠状动脉综合征患者血清可溶性E-选择素和白介素-10水平的变化及其与冠状动脉病变程度的相关性[J].蚌埠医学院学报,2010,35(5):456-458. |
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| 作者姓名： | 汤凤英 马礼坤 石增刚 桑更生 |
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| 作者单位： | 1. 安徽医科大学附属省立医院心血管内科, 安徽合肥 230001;2. 安徽省蚌埠市第三人民医院心血管内科, 安徽蚌埠 233000 |
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| 摘 要： | 目的:探讨急性冠状动脉综合征(acute coronary syndrome,ACS)血清可溶性E-选择素(soluble E-selectin,SES)、白介素-10(interleukin-10,IL-10)水平变化及其与冠状动脉病变程度的相关关系。方法:选择冠状动脉造影患者94例,分为ACS组39例,稳定型心绞痛组(SAP)组23例,正常对照组32例,应用ELISA法测定患者血清SES、IL-10水平;免疫比浊法检测血清超敏C反应蛋白(high-sensitive creactive protein,hs-CRP)。结果:ACS组血清SES、IL-10和hs-CRP水平均明显高于SAP组和对照组(P<0.01)。SAP组SES和hs-CRP水平与对照组比较差异均无统计学意义(P>0.05)。SES、IL-10与冠状动脉病变数量及冠状动脉病变程度均无明显的相关关系(P>0.05)。结论:ACS患者血清SES和IL-10水平明显增高,提示其与斑块的不稳定性有关,而与冠状动脉病变程度无关。
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| 关 键 词： | 心肌缺血 急性冠状动脉综合征 心绞痛 E-选择素 白介素-10 |
| 收稿时间： | 2009-10-29 |
Correlation between serum soluble E-selectin, interleukin-10 and the degree of coronary artery lesions in acute coronary syndrome |
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| TANG Feng-ying,MA Li-kun,SHI Zeng-gang,SANG Geng-sheng.Correlation between serum soluble E-selectin, interleukin-10 and the degree of coronary artery lesions in acute coronary syndrome[J].Journal of Bengbu Medical College,2010,35(5):456-458. |
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| Authors: | TANG Feng-ying MA Li-kun SHI Zeng-gang SANG Geng-sheng |
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| Institution: | 1. Department of Cardiovasology, The Affiliated Provincial Hospital of Anhui Medical University, Hefei Anhui 230001;2. Department of Cardiovasology, Bengbu Third People's Hospital, Bengbu Anhui 233000, China |
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| Abstract: | Objective:To explore the correlation between the levels of soluble E-selectin(SES),interleukin-10(IL-10)and the degree of coronary artery stenosis in acute coronary syndrome(ACS).Methods:Ninety-four patients receiving coronery artery angiography were divided into ACS group(39 cases),stable angina pectoris(SAP)group(23 cases)and control group(32 cases).The serum levels of SES and IL-10 were measured by ELISA,and the high-sensitive creactive protein(hs-CRP)was dertermined by immunoturbidimetry.Results:The ser... |
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| Keywords: | myocardial ischemia acute coronary syndrome soluble E-selectin interleukin-10 |
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