神外病区多重耐药鲍曼不动杆菌医院感染暴发调查与控制

目的研究神经外科住院患者下呼吸道鲍曼不动杆菌医院感染暴发的原因及其危险因素,为制定防控措施提供参考依据。方法通过现场流行病学调查方式,对某医院神经外科一起住院患者鲍曼不动杆菌肺部感染暴发事件进行调查。结果某医院神经外科在6周时间内连续发生9例患者发生多重耐药鲍曼不动杆菌感染,属于医院感染暴发事件。从发生医院感染的9例患者痰标本中均检出同源性鲍曼不动杆菌。所分离的鲍曼不动杆菌只对碳青霉烯类(亚胺培南)抗生素、含有β内酰胺酶抑制剂的复合制剂(头孢哌酮/舒巴坦)敏感,对其他所试验的临床常用抗菌药物全部耐药。结论该医院发生的鲍曼不动杆菌肺部感染属于医院感染暴发,经严格消毒隔离和积极临床治疗,疫情得到有效控制。

INVESTIGATION AND CONTROL OF MULTIRESISTANT ACINETOBACTER NOSOCOMIAL INFECTION IN THE NEUROSURGERY WARD

Objective To investigate the epidemic,risk factors of Acinetobacter Baumannii nosocomial infection of lower respiratory tract in patients in the Neurosurgery Ward,in order to provide reference for preventing and controlling of the nosocomial infection.Methods The on the spot epidemic investigation method was used to observe the pulmonary Acinetobacter Baumannii infection in neurosurgery ward.Results 9 cases multi-resistant Acinetobacter Baumannii nosocomial infection occurred successively in 6 weeks in the department of neurosurgery of some hospital which belonged to outbreak of nosocomial infection.The Acinetobacter Baumannii strains were detected in the phlegm samples of 9 cases inpatients of nosocomial infections.The Acinetobacter Baumannii isolated were sensitive only to Carbapenems antibiotics(imipenem) and compound that containing beta-Lactams enzyme inhibitors(cefoperazone / sulbactam) and were resistant to other clinical commonly used antibiotics tested.Conclusion The pulmonary infection of Acinetobacter Baumannii strains happened in this hospital belongs to outbreak of nosocomial infection.The epidemic in neurosurgery ward can be controlled by completely disinfection and isolation measures and the actively clinical treatment.