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连续性肾脏替代治疗在重症急性肾衰竭中的疗效
引用本文:陈金斌,李明晶,金莎莎,徐小竹.连续性肾脏替代治疗在重症急性肾衰竭中的疗效[J].中国继续医学教育,2021(7).
作者姓名:陈金斌  李明晶  金莎莎  徐小竹
作者单位:当阳市人民医院肾病内科
摘    要:目的探究并对比分析连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾衰的临床效果及其价值。方法选取2012年2月—2019年2月本院收治的60例重症急性肾衰患者作为本次研究的观察对象,根据患者治疗手段的不同将患者分为对照组和实验组,每组各30例,对照组急性肾衰患者给予间歇性血液透析治疗,实验组急性肾衰患者给予连续性肾脏替代治疗,对比两组患者的治疗效果、生化指标、随访存活率。结果实验组患者在接受了连续性肾脏替代治疗后,治疗效果明显好于对照组患者,且生化指标得到了更明显的改善,半年后随访的存活率更高,差异具有统计学意义(P<0.05)。结论连续性肾脏替代治疗与间歇性血液透析用于治疗重症急性肾衰均有一定疗效,但连续性肾脏替代治疗的治疗效果更好,能够显著改善患者的肾功能指标,半年内存活率相对理想,具有较高的临床应用价值。

关 键 词:急性肾衰  间歇性血液透析  连续性肾脏替代治疗  疗效  存活率  预后

Efficacy of Continuous Renal Replacement Therapy in Severe Acute Renal Failure
CHEN Jinbin,LI Mingjing,JIN Shasha,XU Xiaozhu.Efficacy of Continuous Renal Replacement Therapy in Severe Acute Renal Failure[J].China Continuing Medical Education,2021(7).
Authors:CHEN Jinbin  LI Mingjing  JIN Shasha  XU Xiaozhu
Institution:(Department of Nephrology,Dangyang People’s Hospital,Dangyang Hubei 444100,China)
Abstract:Objective To explore and compare the clinical effect and value of continuous renal replacement therapy and intermittent hemodialysis in the treatment of severe acute renal failure.Methods 60 patients with severe acute renal failure who were admitted to our hospital from February 2012 to February 2019 were selected as the observation objects of this study.The patients were divided into control group and experimental group according to the different treatment methods of patients.Thirty patients in each group,the control group was treated with intermittent hemodialysis,while patients with acute renal failure in the experimental group were given continuous renal replacement therapy.The treatment effects,biochemical indicators,and followup survival rates were compared between the two groups.Results After receiving continuous renal replacement therapy in the experimental group,the treatment effect was significantly better than that in the control group,and the biochemical indicators were more significantly improved.The survival rate at the follow-up after six months was higher and the difference was statistically significant(P<0.05).Conclusion Both continuous renal replacement therapy and intermittent hemodialysis can be used to treat severe acute renal failure.However,continuous renal replacement therapy is more effective and can significantly improve the renal function indicators of patients.The relative survival rate within half a year is relatively ideal,with high clinical application value.
Keywords:acute renal failure  intermittent hemodialysis  continuous renal replacement therapy  efficacy  survival rate  prognosis
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