金黄色葡萄球菌的临床分布及耐药性分析

目的 了解金黄色葡萄球菌的临床分布及其耐药情况.方法 对我院2007～2009年分离的金黄色葡萄球菌进行耐药监测.结果 3年共分离出金黄色葡萄球菌106株.在临床标本中,痰液分离率最高,占57.6％；感染分布以呼吸内科为主,占43.4％.MRSA对青霉素类、大环内酯类、氨基糖苷类、喹诺酮类、四环素类、克林霉素的耐药率均很高且明显高于MSSA,并呈现多重耐药；MSSA对青霉素、红霉素、庆大霉素、四环素的耐药率较高在80％左右；MRSA和MSSA对糖肽类、利奎唑胺和奎奴普汀/达福普汀都很敏感.结论 金黄色葡萄球菌耐药严重,特别是对MRSA应引起临床的重视.

Analysis of clinical distribution and drug resistance of staphylococcus aureus

Objective To investigate staphylococcus aureus the purpose of the clinical.Methods All staphylococcus aureus strains were isolated from patients during the period from 2007~2009 in our hospital.Results Three years have been isolated staphylococcus aureus 106 strains.Sputum was the highest in the distribution of 57.6% in clinical specimen;infection,accounting for distribution in the department of respiratory medicine 43.4%.The drug resistant rate of MRSA strains to penicillins、macrolides、aminoglycosides、quinolones、tetracyclines、clindamycin showed highly and was obviously higher than that of MSSA,which could be showing multi-drug resistance.The drug resistant rate of MSSA strains to penicillin,erythromycin,gentamycin,tetracycline showed highly and were 80% or so.MRSA and MSSA were very susceptibility to glycopeptides、linezolid and quinupristin-dalfo-pristin.Conclusions Staphylococcus aureus are severe now,and special attention should be paid to MRSA.It is essential to strengthen monitoring the drug resistance of MRSA.