| The Receptor Role of Glycophorin A during the Invasion of Erythrocytes by Plasmodium Falciparum |
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| 作者姓名： | 张世民 管惟滨 杨志铭 李建新 周元昌 魏尧梅 |
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| 作者单位： | Department of Biochemistry Second Military Medical College，Shanghai，Department of Biochemistry，Second Military Medical College，Shanghai，Department of Biochemistry，Second Military Medical College，Shanghai，Department of Biochemistry，Second Military Medical College，Shanghai，Department of Biochemistry，Second Military Medical College，Shanghai，Department of Biochemistry，Second Military Medical College，Shanghai |
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| 摘 要： | Under the condition of in vitro culture,the effects of glycophorin A(GPA)of human erythrocyte membrane,anti-GPA IgG,α_1-acid glycoprotein,ovomucoid,wheat germ agglutinin,etc.on the invasion of erythrocytes by P.falciparum were observed in this study.The results show that the combination ofGPA with P.falciparum merozoites has high specificity,high affinity and atendency to saturation,and produces specific biological effects.These confirm forthe first time from the characteristics of the ligand-receptor interaction that GPAis a receptor recognized and bound by P.falciparum merozoites.
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The Receptor Role of Glycophorin A during the Invasion of Erythrocytes by Plasmodium Falciparum |
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| Zhang Shimin Guan Weibin Yang Zhiming Li Jianxin Zhou Yuanchang Wei Yaomei.The Receptor Role of Glycophorin A during the Invasion of Erythrocytes by Plasmodium Falciparum[J].Journal of Medical Colleges of PLA(China),1987(2). |
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| Authors: | Zhang Shimin Guan Weibin Yang Zhiming Li Jianxin Zhou Yuanchang Wei Yaomei |
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| Institution: | Zhang Shimin Guan Weibin Yang Zhiming Li Jianxin Zhou Yuanchang Wei Yaomei Department of Biochemistry,Second Military Medical College,Shanghai |
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| Abstract: | |
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| Keywords: | glycophorin A plasmodium falciparum receptor |
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