| PI3K/Akt/mTOR信号转导途径与非小细胞肺癌的关系 |
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| 引用本文： | 岳文涛,王小敏,王玥.PI3K/Akt/mTOR信号转导途径与非小细胞肺癌的关系[J].中国肺癌杂志,2009,12(4). |
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| 作者姓名： | 岳文涛 王小敏 王玥 |
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| 作者单位： | 北京市结核病胸部肿瘤研究所,北京市肿瘤分子生物学实验室肺癌分室(细胞生物学研究室),北京,101149 |
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| 基金项目： | 北京市科技新星项目，教育部出国留学回国启动基金和北京市优秀人才培养基金 |
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| 摘 要： |
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| 关 键 词： | 肺肿瘤 |
The Relationship between the PI3K/Akt/mTOR Signal Transduction Pathway and Non-small Cell Lung Cancer |
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| Wentao YUE,Xiaomin WANG,Yue WANG.The Relationship between the PI3K/Akt/mTOR Signal Transduction Pathway and Non-small Cell Lung Cancer[J].Chinese Journal of Lung Cancer,2009,12(4). |
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| Authors: | Wentao YUE Xiaomin WANG Yue WANG |
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| Institution: | Wentao YUE,Xiaomin WANG,Yue WANG Department of Cellular , Molecular Biology,Beijing TB , Thoracic Tumor Research Institute,Beijing 101149,China |
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| Abstract: | Background and objective It has been known that abnormality of PI3K/Akt/mTOR signal pathway plaied an important role in the oncogenesis of lung cancer.In this study,we tried to detect the mRNA expression levels of VEGF,PI3K,Akt,mTOR gene,the key genes of PI3K/Akt/mTOR signal pathway,in human non-small cell lung cancer(NSCLC) tissue and explore the relationship between PI3K/Akt/mTOR signaling pathway and non-small cell lung cancer.Methods Lung cancer tissue specimens were obtained from 40 patients.Adjacent-t... |
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| Keywords: | VEGF PI3K Akt mTOR |
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