168例剖宫产围手术期预防应用抗菌药物的临床分析

目的了解医院剖宫产围手术期预防应用抗生素药物现状，为加强医院感染管理，促进临床合理应用抗菌药物提供依据。方法随机抽样方法抽取笔者所在医院2004～2007年剖宫产手术病例168例，对围手术期预防用抗生素药物情况进行临床分析。结果围手术期预防用抗生素药物存在问题有：（1）168例剖宫产病例全部应用了抗生素，其使用率100％；（2）初次给药时机不适，未在麻醉诱导时初次用药且绝大多数为术后初次用药（77．38％）；（3）总的用药时间偏长，〉72h者达94．65％；（4）选择用药的合理性有待提高。结论应将合理用药纳入医院管理年考评标准和产科医师继续医学教育内容，进一步规范医师临床用药行为。

168 cases of cesarean section on the prevention of perioperative application of antibiotics in clinical analysis

Objective It aims to understand the present situation of the preventative application of antibiotics during the cesarean section , improve the infection control in hospital as well as provide reference to promote the reasonably clinical application of antibacterial drugs. Methods Use the random sampling method drawn from 168 cases of the cesarean section during 2004 - 2007 and make the clinical analysis to the preventive application of antibiotic drugs on the surgical period. Re- suits The problems of the preventative application of antibiotics on the surgical period were ： （ 1 ） the full use of antibiotics in the 168 cases of the cesarean section with the pecentage of 100% ; （2） the wrong time of the initial delivery because the ini- tial delievery most happened after surgeries （77. 38% ） instead of the period of the narcotic guide; （3）the long total time of druge use, 94.65% cases were 〉 72h ; （4） the legitimacy of the medicine choice. Conclusion It is well advised that rational medicine use should be included in the appraisal criteria of hospital management and the further medical education of obstetrics doctors as well as further standardize the clinical behaviors of medicine doctors.