出生体重、孕周对学龄儿童肺功能的影响

目的研究出生体重、孕周与学龄儿童肺功能测定指标之间的关系。方法测定35名6～9岁低出生体重儿的身高、体重、肺功能，调查孕周以及被动吸烟情况，并与年龄、性别配对的正常出生体重儿童进行比较。结果(1)低出生体重组儿童的用力肺活量(FVC)、一秒钟用力呼气容积(FEV

The effects of low birth weight, gestational age on lung function in childhood

OBJECTIVE: To evaluate the effects of low birth weight, gestational age on lung function in later childhood. METHODS: Height, body weight and lung function were measured in a cohort of 35 children with low birth weight (aged 6 approximately 9 y) and 35 healthy controls matched for sex and age with normal birth weight. At the same time, we inquired their gestational age and passive smoking history. The correlation analysis was used to analyze the relationship between lung function in these children and birth weight and gestational age. RESULTS: FVC, FEV(1), FEV(1)% pred, V(75), V(50), V(50%) Pred, (V(25%) Pred in children with low birth weight were significantly lower than those in children with normal birth weight (P < 0.05). The lung function statistically positively correlated with birth weight (r = 0.245 approximately 0.365, P < 0.05), but not with gestational age (P > 0.05). CONCLUSION: Low birth weight was positively correlated with most lung function parameters in childhood.