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EphB4在乳腺浸润性导管癌中的表达及意义
引用本文:杨光伦,涂刚,姚榛祥,岳俊伊. EphB4在乳腺浸润性导管癌中的表达及意义[J]. 第三军医大学学报, 2009, 31(5)
作者姓名:杨光伦  涂刚  姚榛祥  岳俊伊
作者单位:重庆医科大学附属第一医院普外科,重庆,400016
摘    要:目的 探讨EphB4在乳腺浸润性导管癌中的表达及临床意义.方法 采用免疫组织化学S-P法榆测65例浸润性导管癌以及12例癌旁乳腺组织中的EphB4、ER、PR、CerBb-2、P53的表达.结果 EphB4在65例乳腺浸润性导管癌中的表达明显高于癌旁乳腺组织(P<0.05),EphB4的表达与CerBb-2及肿瘤组织学分级呈正相关(P<0.05);与ER、PR及淋巴结转移元相关性(P>0.05).结论 EphB4 在乳腺癌的发展中起着重要作用.

关 键 词:乳腺浸润性导管癌

Expression and clinical significance of EphB4 in breast infiltrating ductal carcinoma:report of 65 cases
YANG Guang-lun,TU Gang,YAO Zhen-xiang,YUE Jun-yi. Expression and clinical significance of EphB4 in breast infiltrating ductal carcinoma:report of 65 cases[J]. Acta Academiae Medicinae Militaris Tertiae, 2009, 31(5)
Authors:YANG Guang-lun  TU Gang  YAO Zhen-xiang  YUE Jun-yi
Affiliation:YANG Guang-lun,TU Gang,YAO Zhen-xiang,YUE Jun-yi(Department of General Surgery,First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China)
Abstract:Objective To study the expression and clinical significance of EphB4 in breast infiltrating ductal carcinoma.MethodsSP immunohistochemical technique was used to examine the expression of EphB4 in 65 cases of breast infiltrating ductal cancer and 12 matched adjacent tissue samples.ResultsThe level of EphB4 in breast infiltrating ductal cancer was significantly higher than that of adjacent normal tissues(P<0.01).EphB4 expression had a positive correlation with histological grade and CerBb-2(P<0.05),but not wi...
Keywords:EphB4
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